SIRT1 / Sirtuin 1

sirtuin 1

The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR. SIRT1 also regulates the p53-dependent DNA damage response pathway by binding to and deacetylating p53.

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Products

Antibodies (108)

ELISA Kits (17)

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Over-Expression Cell Culture Supernatant (1)

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SIRT1 / Sirtuin 1 (136)

Reactivity

Human (104)

Mouse (38)

Rat (24)

Amphibian (1)

Bat (5)

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IHC-plus™ SIRT1 / Sirtuin 1 Antibody (clone 7B7) LS-B4520

(5.0) Rating

(1) Publication(s)

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal (7B7) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ SIRT1 / Sirtuin 1 Antibody (aa577-590) LS-B8356

(5.0) Rating

(1) Publication(s)

Antibody:

SIRT1 / Sirtuin 1 Goat anti-Human Polyclonal (aa577-590) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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SIRT1 / Sirtuin 1 Antibody (aa207-256) LS-B1564

(4.3) Rating

(4) Publication(s)

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (aa207-256) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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IHC-plus™ SIRT1 / Sirtuin 1 Antibody (C-Terminus) LS-B1895

(5.0) Rating

(1) Publication(s)

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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SIRT1 / Sirtuin 1 Antibody (aa207-256) LS-C31402

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (aa207-256) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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Human SIRT1 / Sirtuin 1 (Sandwich ELISA) ELISA Kit - LS-F12606

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Rat SIRT1 / Sirtuin 1 (Sandwich ELISA) ELISA Kit - LS-F21634

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse SIRT1 / Sirtuin 1 (Sandwich ELISA) ELISA Kit - LS-F21345

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human SIRT1 / Sirtuin 1 (Sandwich ELISA) ELISA Kit - LS-F22088

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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SIRT1 / Sirtuin 1 Antibody (clone 1F3) LS-C359279

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal (1F3) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ELISA, Flo, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

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SIRT1 / Sirtuin 1 Antibody (clone 1F3) LS-C169237

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal (1F3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$435

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Human SIRT1 / Sirtuin 1 (Sandwich ELISA) ELISA Kit - LS-F6780

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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SIRT1 / Sirtuin 1 Antibody LS-C115840

Antibody:

SIRT1 / Sirtuin 1 Chicken anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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SIRT1 / Sirtuin 1 Antibody (30-110 aa) LS-C381089

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (30-110 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SIRT1 / Sirtuin 1 Antibody (phospho-Ser47) LS-C416846

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (pSer47) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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SIRT1 / Sirtuin 1 Antibody (aa41-90) LS-C200670

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (aa41-90) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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SIRT1 / Sirtuin 1 Antibody (clone 1F3) LS-C758864

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal (1F3) Antibody

Reactivity:

Human, Non-Human Primate

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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SIRT1 / Sirtuin 1 Antibody LS-C192676

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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SIRT1 / Sirtuin 1 Antibody LS-C812768

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human, Monkey

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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SIRT1 / Sirtuin 1 Antibody (phospho-Ser47) LS-C801221

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (pSer47) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SIRT1 / Sirtuin 1 Antibody LS-C484772

Antibody:

SIRT1 / Sirtuin 1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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SIRT1 / Sirtuin 1 Antibody LS-C746926

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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SIRT1 / Sirtuin 1 Antibody (aa236-490) LS-C296443

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Mouse Polyclonal (aa236-490) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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SIRT1 / Sirtuin 1 Antibody (clone 032, Preservative Free) LS-C819164

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Monoclonal (Preservative Free) (032) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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SIRT1 / Sirtuin 1 Antibody (Preservative Free) LS-C818303

Antibody:

SIRT1 / Sirtuin 1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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