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OCLN / Occludin
occludin
OCLN / Occludin is an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
| Gene Name: | occludin |
| Synonyms: | OCLN, Occludin, BLCPMG |
| Target Sequences: | NM_002538 NP_002529.1 Q16625 |
Publications (8)
1
The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination With Cell Polarization During Ameloblast Differentiation. Otsu K, Ida-Yonemochi H, Fujiwara N, Harada H. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2016 November;31:1943-1954. (Human)
[Full Text Article]
[PubMed:27218883]
Related Antibodies: LS-B2320.
2
TLR3 deficiency exacerbates the loss of epithelial barrier function during genital tract Chlamydia muridarum infection. Kumar R, Gong H, Liu L, Ramos-Solis N, Seye CI, Derbigny WA. PloS one. 2019 January;14:e0207422. [Full Text Article]
[PubMed:30625140]
[PMC:PMC6326510]
Related Antibodies: LS-B2187.
3
Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1. Morgan Wong, Ashwinkumar Subramenium Ganapathy, Eric Suchanec, Laura Laidler, Thomas Ma, Prashant Nighot. American journal of physiology. Cell physiology. 2019 May;316:C753-C765. [Full Text Article]
[PubMed:30892937]
[PMC:PMC6580157]
Related Antibodies: LS-C140253.
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(88)
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OCLN / Occludin Mouse anti-Human Monoclonal (C-Terminus) (OC-3F10) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$485
Neuroscience
OCLN / Occludin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IHC-P, IP, WB
Unconjugated
50 µg/$485
Neuroscience
OCLN / Occludin Rabbit anti-Human Polyclonal (aa35-84) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OCLN / Occludin Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
OCLN / Occludin Guinea pig anti-Human Polyclonal (aa358-504) Antibody
Mouse, Dog, Rat, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$554
OCLN / Occludin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Neuroscience
OCLN / Occludin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
OCLN / Occludin Mouse anti-Human Monoclonal (C-Terminus) (FITC) (OC-3F10) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, WB
FITC Conjugated
100 µg/$919
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
OCLN / Occludin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, WB
Unconjugated
0.25 ml/$528
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
HEK 293 Cells
Myc-DDK (Flag)
59 kDa
20 µg/$1,107
OCLN / Occludin Rabbit anti-Human Polyclonal (aa446-474) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
![OCLN / Occludin Antibody - Immunofluorescence of monoclonal antibody to OCLN on HeLa cell. [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/ocln-occludin-antibody-clone-1g7-ls-c197814/145875_5076948.jpg)
OCLN / Occludin Mouse anti-Human Monoclonal (1G7) Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$423
OCLN / Occludin Mouse anti-Human Monoclonal (C-Terminus) (AF488) (OC-3F10) Antibody
Mouse, Dog, Rat, Human
ELISA, ICC, IF, WB
AF488 Conjugated
100 µg/$520
OCLN / Occludin Mouse anti-Human Monoclonal (C-Terminus) (AF594) (OC-3F10) Antibody
Mouse, Dog, Rat, Human
ELISA, ICC, IF, WB
AF594 Conjugated
100 µg/$566
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
293T Cells
Myc-DDK (Flag)
59 kDa
20 µg/$150
OCLN / Occludin Mouse anti-Human Monoclonal (C-Terminus) (HRP) (OC-3F10) Antibody
Mouse, Dog, Rat, Human
ELISA, WB
HRP Conjugated
100 µg/$842
OCLN / Occludin Rabbit anti-Mouse Polyclonal (aa17-107) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
OCLN / Occludin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
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of 93
product results
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