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NPM1 / NPM / Nucleophosmin
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
| Gene Name: | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
| Synonyms: | NPM1, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, B23, Nucleophosmin |
| Target Sequences: | NM_002520 NP_002511.1 P06748 |
☰ Filters
Products
Antibodies
(113)
Type
Primary
(113)
Target
NPM1 / NPM / Nucleophosmin
(113)
Reactivity
Human
(104)
Mouse
(81)
Rat
(42)
Bat
(1)
Bovine
(7)
Chicken
(1)
Chimpanzee
(9)
Dog
(8)
Gibbon
(9)
Goat
(3)
Guinea pig
(3)
Hamster
(2)
Horse
(9)
Monkey
(12)
Orangutan
(6)
Pig
(13)
Rabbit
(13)
Xenopus
(1)
Application
IHC
(40)
IHC-Fr
(4)
IHC-P
(36)
WB
(103)
Flo
(6)
ELISA
(20)
ICC
(13)
IF
(29)
IP
(9)
Peptide-ELISA
(9)
Host
rabbit
(91)
mouse
(21)
goat
(1)
Product Group
IHCPlus
(3)
PathPlus Cancer
(4)
PathPlus Cancer Pathology
(4)
Isotype
IgG
(37)
IgG1
(6)
IgG1,k
(6)
IgG2a
(1)
IgG2b,k
(4)
Clonality
monoclonal mc
(21)
polyclonal pc
(92)
Clone
1042CT5.2.1
(1)
3B2
(1)
5E3
(1)
7H10B9
(2)
AT23F1
(1)
FC-61991
(1)
NA24
(2)
NPM1/1902
(3)
Format
APC
(4)
APC Conjugated
(4)
Azide-free
(2)
Biotin Conjugated
(8)
BSA-free
(2)
Concentrated
(1)
Cy3 Conjugated
(4)
Cy7 Conjugated
(4)
DY488 Conjugated
(1)
DY550 Conjugated
(1)
DY650 Conjugated
(1)
FITC Conjugated
(7)
HRP Conjugated
(7)
PE Conjugated
(4)
Ready-to-Use
(2)
Unconjugated
(72)
Epitope
aa20-154
(16)
aa204-290
(8)
aa212-292
(8)
pThr199
(7)
N-Terminus
(6)
C-Terminus
(5)
aa178-227
(4)
aa87-136
(4)
pThr234
(4)
180-260 aa
(2)
aa250-294
(2)
10-90 aa, N-terminal
(1)
140-220 aa
(1)
Glu22
(1)
Lys230
(1)
aa1-209
(1)
aa1-294
(1)
aa1-50
(1)
aa100-150
(1)
aa171-220
(1)
aa181-230
(1)
aa198-226
(1)
aa200-250
(1)
aa201-250
(1)
aa21-38
(1)
aa22-41
(1)
aa281-294
(1)
aa7-33
(1)
aa81-294
(1)
p199
(1)
p234
(1)
Publications
No
(113)
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal (7H10B9) Antibody
Human, Monkey
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$380
Cancer Pathology
Cancer
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal (AT23F1) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
![NPM1 / NPM / Nucleophosmin Antibody - Immunofluorescence of monoclonal antibody to NPM1 on HeLa cell. [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/npm1-npm-nucleophosmin-antibody-clone-3b2-ls-c133351/51336_5015706.jpg)
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal (3B2) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
Cancer Pathology
Cancer
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal Antibody
Mouse, Human
ICC, IHC-P, WB
Unconjugated
50 µl/$460
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
NPM1 / NPM / Nucleophosmin Goat anti-Human Polyclonal (aa281-294) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal (aa81-294) (5E3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (C-Terminus) (DY650) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, IP, WB
DY650 Conjugated
0.1 ml/$416
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (C-Terminus) (DY488) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, IP, WB
DY488 Conjugated
0.1 ml/$416
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, IP, WB
DY550 Conjugated
0.1 ml/$416
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Cancer Pathology
Cancer
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa7-33) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (pThr199) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (pThr199) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NPM1 / NPM / Nucleophosmin Mouse anti-Human Monoclonal Antibody
Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa1-209) Antibody
Human
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$450
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (pThr199) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (pThr199) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa200-250) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa22-41) Antibody
Rabbit, Mouse, Rat, Pig, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Cancer Pathology
Cancer
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (aa204-290) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
NPM1 / NPM / Nucleophosmin Rabbit anti-Human Polyclonal (pThr199) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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of 113
product results
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