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ITGB4 / Integrin Beta 4
integrin, beta 4
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Gene Name: | integrin, beta 4 |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4 |
| Target Sequences: | NM_000213 NP_000204.3 P16144 |
Publications (3)
1
Role of Integrin ß4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress. Chen W, Epshtein Y, Ni X, Dull RO, Cress AE, Garcia JG, Jacobson JR. Scientific reports. 2015 5:16529. (IP; Human)
[Full Text Article]
[PubMed:26572585]
[PMC:PMC4647208]
Related Antibodies: LS-C14098.
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article]
[PubMed:31771627]
[PMC:PMC6878650]
Related Antibodies: LS-B3778.
3
A case of oral mucous membrane pemphigoid with IgG antibodies to integrin alpha 6 beta 4. Miyamoto S, Chikazu D, Yasuda T, Enomoto A, Oh-i T, Hirako Y, Tsuchisaka A, Yasukochi A, Sogame R, Teye K, Koga H, Ishii N, Qian H, Li X, Hashimoto T. The British journal of dermatology. 1995 Dec;171:1555-7. [Full Text Article]
[PubMed:24836504]
Related Antibodies: LS-B9845.
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(105)
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(81)
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(29)
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(16)
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(50)
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(62)
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(9)
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(34)
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(41)
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(102)
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(3)
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(2)
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(1)
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(5)
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Human
(5)
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(1)
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(2)
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293T Cells
(2)
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(4)
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(3)
Wheat Germ Extract
(1)
Purification
Purified
(2)
ITGB4 / Integrin Beta 4 Rat anti-Human Monoclonal (439-9B) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$460
ITGB4 / Integrin Beta 4 Rat anti-Human Monoclonal (Biotin) (439-9B) Antibody
Human
Flo
Biotin Conjugated
100 µg/$396
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (aa1619-1822) (10B10D5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (450-9D) Antibody
Human
Flo, IF, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Azide-free) (450-9D) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free
500 µg/$668
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (UM-A9) Antibody
Human
Block, Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (aa1809-1822) Antibody
Rat, Human
IHC, IHC-Fr, IP
Unconjugated
100 µl/$842
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (aa28-710) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$896
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (aa1481-1530) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Human
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
100 µg/$854
ITGB4 / Integrin Beta 4 Sheep anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$919
ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (346-11A) Antibody
Mouse
IHC, IHC-Fr, IP, WB
Unconjugated
500 µg/$558
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IP
Biotin Conjugated
100 µl/$1,054
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Amino Acid: 1619-1822) (10B10D5) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
100 µg/$626
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (pY1510) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (FITC) (UMA9) Antibody
Human
Flo, Func, WB
FITC Conjugated
120 Tests/$511
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (1D6B4) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (5G3G5) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (58XB4) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$424
ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (346-11A) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$448
ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (346-11A) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.5 mg/$403
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
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