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| Catalog Number | Size | Price |
|---|---|---|
| LS-C499158-50 | 50 µg | $294 |
| LS-C499158-100 | 100 µg (3.5 mg/ml) | $360 |
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Polyclonal Rabbit anti‑Human ITGB4 / Integrin Beta 4 Antibody (IHC, IF, WB) LS‑C499158
Polyclonal Rabbit anti‑Human ITGB4 / Integrin Beta 4 Antibody (IHC, IF, WB) LS‑C499158
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Integrin Beta 4 antibody LS-C499158 is an unconjugated rabbit polyclonal antibody to Integrin Beta 4 (ITGB4) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Target
Human ITGB4 / Integrin Beta 4
Synonyms
ITGB4 | CD104 | Integrin beta-4 | Integrin Beta 4 | gp150 | CD104 antigen | Integrin beta-4 subunit | Integrin, beta 4
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Integrin beta-4 protein (1401-1533AA)
Specificity
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGB4 / Integrin Beta 4
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
ICC, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
ICC, Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/18/2024
Date Requested: 12/18/2024
