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CD3E

CD3e molecule, epsilon (CD3-TCR complex)

CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Gene Name: CD3e molecule, epsilon (CD3-TCR complex)
Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon, CD3
Target Sequences: NM_000733 NP_000724.1

Publications (1)

1
Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer. Kristina Witt , Susan Evans-Axelsson, Andreas Lundqvist, Martin Johansson, Anders Bjartell, Rebecka Hellsten. Cancer immunology, immunotherapy : CII. 2021 Nov;;70:3155-3166. [Full Text Article] [PubMed:33786638] [PMC:PMC8505385] Related Antibodies: LS-C343957.

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Antibodies (242)
Proteins (22)
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CD3E (273)
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400 (2)
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CD3E Antibody - CD3 epsilon antibody IHC-paraffin: Human Tonsil Tissue.
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CD3E Rabbit anti-Human Polyclonal (aa23-207) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CD3E Antibody - IHC of paraffin-embedded Human tonsil using anti-CD3E mouse monoclonal antibody.
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CD3E Mouse anti-Human Monoclonal (OTI3E10) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
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CD3E Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, WB
Unconjugated
100 µg/$558
Select
CD3E Mouse anti-Human Monoclonal (Biotin) (UCHT1 ) Antibody
Human
Flo, IHC
Biotin Conjugated
100 µg/$626
Select
CD3E Mouse anti-Pig Monoclonal (FITC) Antibody
Pig
Flo, IHC, IHC-Fr, IP
FITC Conjugated
500 µg/$642
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CD3E Rat anti-Mouse Monoclonal (FITC) (YCD3-1) Antibody
Mouse
Flo, IHC, IP
FITC Conjugated
100 µg/$429; 500 µg/$666
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CD3E Mouse anti-Human Monoclonal (FITC) (UCHT1 ) Antibody
Human
Flo, IHC, IHC-Fr, IP
FITC Conjugated
100 Tests/$439
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CD3E Mouse anti-Pig Monoclonal (PE, Cy5) (PPT3) Antibody
Pig
Flo, IHC, IHC-Fr, IP
PE, Cy5 Conjugated
100 µg/$548
CD3E Antibody - IHC staining of FFPE human tonsil using anti-CD3E clone UMAB48 mouse monoclonal antibody at 1:200 and detection with Polink2 Broad HRP DAB.requires heat-induced epitope retrieval with Citrate pH6.O. The image shows strong membranous and cytoplasmic staining.
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CD3E Mouse anti-Human Monoclonal (Carrier-free) (UMAB54) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
CD3E Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
11.9 kDa
100 µg/$499; 20 µg/$364; 1 mg/$1,683
CD3E Antibody - Porcine peripheral blood lymphocytes were stained with Mouse Anti-Porcine CD3e-APC and Mouse Anti-Porcine CD4-FITC.
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CD3E Mouse anti-Pig Monoclonal (APC) (PPT3) Antibody
Pig
Ctox, Flo, IHC-Fr, IHC-P, IP, WB
APC Conjugated
0.1 mg/$497
CD3E Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Fast Shipping
CD3E Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
CD3E Antibody - Intracellular staining of human peripheral blood with anti-CD3 epsilon activation epitope (APA1/1) purified, GAM-FITC.
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CD3E Mouse anti-Human Monoclonal (APA1/1) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$316
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CD3E Mouse anti-Pig Monoclonal (PE) (PPT3) Antibody
Pig
Flo
PE Conjugated
0.1 mg/$400
CD3E Protein
Select
CHO Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD3E consists of 115 amino acids and predicts a molecular mass of 13.2 kDa.
50 µg/$395; 500 µg/$1,641
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CD3E Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$434
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CD3E Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated, Azide-free
100 µg/$394; 500 µg/$666
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CD3E Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, IHC, IP
Unconjugated
500 µg/$493
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CD3E Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
Flo, IHC, IP
Unconjugated, Azide-free
100 µg/$1,315
CD3E Antibody - Immunohistochemistry of paraffin-embedded mouse spleen using CD3E antibody at dilution of 1:100 (40x lens).
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CD3E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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CD3E Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$567; 1 mg/$1,079
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CD3E Hamster anti-Mouse Monoclonal (145-2C11) Antibody
Mouse
Flo, IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$562; 250 µg/$755
Select
CD3E Hamster anti-Mouse Monoclonal (145-2C11) Antibody
Mouse
Flo, IF, IHC, IP, WB
Unconjugated
25 µg/$219; 100 µg/$235
Select
CD3E Hamster anti-Mouse Monoclonal (145-2C11) Antibody
Mouse
Flo, IHC, IP, WB
Unconjugated
500 µg/$463
CD3E Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Viewing 1-25 of 273 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).