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CANX / Calnexin

calnexin

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gene Name: calnexin
Synonyms: CANX, CNX, Calnexin, IP90, p90
Target Sequences: NM_001746 NP_001737.1 P27824

Publications (5)

1
Characterization of zebrafish von Willebrand factor reveals conservation of domain structure, multimerization, and intracellular storage. Ghosh A, Vo A, Twiss BK, Kretz CA, Jozwiak MA, Montgomery RR, Shavit JA. Advances in hematology. 2012 2012:214209. (ICC; Human) [PubMed:23049555] [PMC:PMC3462383]
2
Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins. Wang M, Jokinen J, Tretyakova I, Pushko P, Lukashevich IS. Vaccine. 2018 36:683-690. (WB; Human) [Full Text Article] [PubMed:29287681] Related Antibodies: LS-B6014.
3
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. Luis V Nobre, Katie Nightingale, Benjamin J Ravenhill, Robin Antrobus, Lior Soday, Jenna Nichols, James A Davies, Sepehr Seirafian, Eddie Cy Wang, Andrew J Davison, Gavin Wg Wilkinson, Richard J Stanton, Edward L Huttlin, Michael P Weekes. eLife. 2019 Dec;8:e49894. [Full Text Article] [PubMed:31873071] [PMC:PMC6959991] Related Antibodies: LS-B6881.
4
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy. Marieke C Verweij , Scott G Hansen , Ravi Iyer , Nessy John , Daniel Malouli, David Morrow, Isabel Scholz, Jennie Womack, Shaheed Abdulhaqq, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Julia C Ford, Andrea N Selseth, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Jason Shao, Jonah B Sacha, Michael K Axthelm, Paul T Edlefsen, Jeffrey D Lifson, Louis J Picker, Klaus Früh. Science (New York, N.Y.). 2021 April;372:eabe9233. [Full Text Article] [PubMed:33766941] [PMC:PMC8354429] Related Antibodies: LS-B12410.
5
Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection. Jonas D Albarnaz , Joanne Kite , Marisa Oliveira , Hanqi Li, Ying Di, Maria H Christensen, Joao A Paulo, Robin Antrobus, Steven P Gygi, Florian I Schmidt, Edward L Huttlin, Geoffrey L Smith, Michael P Weekes. Nature communications. 2023 December;14:8134. [Full Text Article] [PubMed:38065956] [PMC:PMC10709566] Related Antibodies: LS-B6881.
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☰ Filters
Products
Antibodies (131)
Primary (131)
CANX / Calnexin (131)
Human (128)
Mouse (84)
Rat (55)
Avian (1)
Bat (7)
Bovine (40)
Chicken (29)
Chimpanzee (3)
Dictyostelium (1)
Dictyostelium discoideum (1)
Dog (34)
Drosophila (21)
Fish (1)
Gibbon (6)
Goat (1)
Guinea pig (36)
Hamster (26)
Horse (4)
Monkey (35)
Orangutan (6)
Pig (70)
Primate (1)
Quail (20)
Rabbit (35)
Sheep (30)
Xenopus (24)
Zebrafish (5)
IHC (59)
IHC-P (37)
WB (125)
Flo (15)
ELISA (21)
ICC (37)
IF (30)
IP (29)
Peptide-ELISA (4)
rabbit (101)
mouse (27)
goat (3)
Product Group
IHCPlus (6)
PathPlus Cancer (11)
Ig (1)
IgG (28)
IgG1 (1)
IgG1,k (3)
IgG2a (1)
IgG2b (3)
IgG2b,k (11)
monoclonal mc (27)
polyclonal pc (104)
1D4 (1)
3H4A7 (2)
4F10 (1)
AT18B9 (1)
C2A1 (1)
CANX/1541 (2)
CANX/1543 (2)
APC (5)
APC Conjugated (7)
Atto 390 Conjugated (2)
Atto 488 Conjugated (2)
Atto 594 Conjugated (2)
Azide-free (3)
Biotin Conjugated (12)
BSA-free (2)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (10)
HRP Conjugated (8)
PE Conjugated (5)
PerCP Conjugated (2)
Preservative Free (1)
RPE Conjugated (2)
Unconjugated (63)
C-Terminus (19)
aa239-461 (8)
aa263-482 (8)
aa251-300 (4)
aa480-529 (4)
pSer583 (3)
520-600 aa (2)
Asp577 (1)
CEAAEERPWLWVVYILTVAL (1)
N-Terminus (1)
aa1-50 (1)
aa200-250 (1)
aa300-350 (1)
aa50-68 (1)
aa500-C-term (1)
aa542-592 (1)
aa543-592 (1)
aa575-593 (1)
p583 (1)
No (128)
Yes (3)
CANX / Calnexin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CANX / Calnexin Goat anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
200 µg/$460
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer
CANX / Calnexin Mouse anti-Human Monoclonal (1D4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Cancer
CANX / Calnexin Rabbit anti-Human Polyclonal (aa500-C-term) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CANX / Calnexin Rabbit anti-Rat Polyclonal (Biotin) Antibody
Mouse, Rat, Hamster, Human
ICC, IF, IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
CANX / Calnexin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CANX / Calnexin Goat anti-Human Polyclonal (aa200-250) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Pig, Horse, Bat, Human, Monkey
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
CANX / Calnexin Antibody - Anti-CANX / Calnexin antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer
CANX / Calnexin Goat anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
200 µg/$460
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CANX / Calnexin Mouse anti-Human Monoclonal (3H4A7) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$485
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
CANX / Calnexin Rabbit anti-Dog Polyclonal Antibody
Xenopus, Rat, Hamster, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$495
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CANX / Calnexin Rabbit anti-Dog Polyclonal (N-Terminus) Antibody
Xenopus, Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer
CANX / Calnexin Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
CANX / Calnexin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CANX / Calnexin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Human
ICC, IF, IHC-P, IP, WB
Unconjugated
50 µl/$460
CANX / Calnexin Antibody
Select
CANX / Calnexin Mouse anti-Human Monoclonal (4F10) Antibody
Human
ICC, IP, WB
Unconjugated
100 µg/$392
CANX / Calnexin Antibody - Anti-Calnexin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
CANX / Calnexin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Quail, Pig, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
CANX / Calnexin Rabbit anti-Human Polyclonal (Biotin) Antibody
Xenopus, Quail, Chicken, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
ICC, IHC, WB
Biotin Conjugated
200 µl/$529
CANX / Calnexin Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CANX / Calnexin Rabbit anti-Human Polyclonal (aa543-592) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$460
CANX / Calnexin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CANX / Calnexin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
CANX / Calnexin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CANX / Calnexin Mouse anti-Human Monoclonal Antibody
Mouse, Goat, Bovine, Pig, Human
IHC-P, WB
Unconjugated
50 µl/$460
CANX / Calnexin Antibody - Calnexin, Rat tissue mix.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CANX / Calnexin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Quail, Pig, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey
Flo, WB
Unconjugated
50 µg/$331; 200 µg/$477
CANX / Calnexin Antibody - Calnexin, Rat tissue mix.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CANX / Calnexin Rabbit anti-Dog Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Quail, Chicken, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
Flo, ICC, IHC, IP, WB
Biotin Conjugated
200 µg/$539
Select
CANX / Calnexin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
40 µg/$485
CANX / Calnexin Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer using CANX Antibody at dilution of 1:100
Select
CANX / Calnexin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
CANX / Calnexin Antibody - IHC testing of FFPE human small intestine carcinoma with Calnexin antibody. HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min.
Select
CANX / Calnexin Mouse anti-Human Monoclonal (CANX/1541) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CANX / Calnexin Antibody - IHC testing of FFPE human small intestine carcinoma with Calnexin antibody. HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min.
Select
CANX / Calnexin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CANX/1541) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CANX / Calnexin Antibody - Western blot of recombinant CANX / Calnexin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CANX / Calnexin Rabbit anti-Mouse Polyclonal (aa263-482) (FITC) Antibody
Mouse, Pig, Human
WB
FITC Conjugated
100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$794; 2 ml/$1,031; 5 ml/$1,804
CANX / Calnexin Antibody - Immunohistochemical analysis of Calnexin (pS583) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CANX / Calnexin Rabbit anti-Human Polyclonal (pSer583) Antibody
Mouse, Dog, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).