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| Catalog Number | Size | Price |
|---|---|---|
| LS-B12416-100 | 100 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CANX / Calnexin Antibody (aa543‑592, IHC, IF, WB) LS‑B12416
PathPlus™ Polyclonal Rabbit anti‑Human CANX / Calnexin Antibody (aa543‑592, IHC, IF, WB) LS‑B12416
Note: This antibody replaces LS-C117633
Antibody:
CANX / Calnexin Rabbit anti-Human Polyclonal (aa543-592) Antibody
Application:
IHC, IHC-P, IF, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CANX / Calnexin Rabbit anti-Human Polyclonal (aa543-592) Antibody
Application:
IHC, IHC-P, IF, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
CANX (also called calnexin) is a calcium-binding molecular chaperone protein that is involved in facilitating the assembly and folding of newly synthesized N-linked glycoproteins. It is a stress-induced protein located in the endoplasmic reticulum membrane. It is also found in melanosomes, where it appears to be involved in melanosome biogenesis. CANX is broadly expressed in normal and diseased tissues, and expression may be increased or decreased in certain types of cancers.
References: EMBO J. 2012;31(7):1823-1835. doi: 10.1038/emboj.2012.15; J Proteome Res. 2003;2(1):69-79. PMID: 12643545; J Transl Med. 2016;14(1):196. doi: 10.1186/s12967-016-0948-z; Cancer Lett. 2004;203(2):225-231. PMID: 14732231; Lung Cancer. 2015;90(2):342-345. doi: 10.1016/j.lungcan.2015.08.015; J Cell Mol Med. 2017;21(12):3141-3149. doi: 10.1111/jcmm.13413.
Target
Human CANX / Calnexin
Synonyms
CANX | CNX | Calnexin | IP90 | p90
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human Calnexin. (AA Range: 543-592)
Epitope
aa543-592
Specificity
This antibody detects endogenous levels of total Calnexin protein.
Applications
- IHC
- IHC - Paraffin (1:50)
- Immunofluorescence (1:100 - 1:500)
- Western blot (1:500 - 1:1000)
- Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Predicted MW 67 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CANX / Calnexin
Validation
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ CANX / Calnexin Antibody (aa543-592) for IHC, IF/Immunofluorescence, WB/Western LS-B12416 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Monkey, Mouse, Bat, Bovine, Dog, Horse, Pig, Rabbit, Chicken
Applications:
IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/12/2024
Date Requested: 11/12/2024
