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Vimentin
Vimentin is a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
| Gene Name: | Vimentin |
| Synonyms: | VIM, Vimentin, vimenin |
| Target Sequences: | NM_003380 NP_003371.2 P08670 |
Publications (11)
1
Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Rankin EB, Tomaszewski JE, Haase VH. Cancer research. 2006 66:2576-83.
[PubMed:16510575]
[PMC:PMC3514875]
2
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. Genes & development. 2007 21:2788-803.
[PubMed:17974918]
[PMC:PMC2045132]
3
Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation. Johnstone CN, Mongroo PS, Rich AS, Schupp M, Bowser MJ, Delemos AS, Tobias JW, Liu Y, Hannigan GE, Rustgi AK. Molecular and cellular biology. 2008 28:687-704.
[PubMed:17998334]
[PMC:PMC2223422]
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Vimentin Mouse anti-Human Monoclonal (RV203) Antibody
Goat, Dog, Rat, Hamster, Pig, Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$485
Vimentin Chicken anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P
Unconjugated
0.1 ml/$460
Vimentin Mouse anti-Pig Monoclonal (V9) Antibody
Chicken, Sheep, Rat, Pig, Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
Vimentin Mouse anti-Human Monoclonal (VI-10) Antibody
Chicken, Porcine, Rat, Mouse, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
Cancer Pathology
Cancer
Vimentin Mouse anti-Human Monoclonal (23H2) Antibody
Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Cancer Pathology
Cancer
Vimentin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Vimentin Mouse-Balb/c anti-Dog Monoclonal (FITC) (RV202) Antibody
Chicken, Zebrafish, Pig, Rat, Mouse, Goat, Dog, Human, Monkey
Flo, ICC, IHC, IHC-Fr
FITC Conjugated
1 ml/$481
Vimentin Rabbit anti-Human Polyclonal (APC) Antibody
Human
Flo, IHC, WB
APC Conjugated
200 µl/$952
Vimentin Rabbit anti-Human Polyclonal (aa300-350) Antibody
Human
ELISA, IHC, WB
Unconjugated
40 µg/$485
Sandwich
96-Well Strip Plate
Human
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
E. coli
His, N-Terminal
55.1kDa
10 µg/$282; 50 µg/$450; 200 µg/$897; 100 µg/$717; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
Vimentin Mouse anti-Pig Monoclonal (Azide-free) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Cat, Horse, Gerbil, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P
Unconjugated, Azide-free
50 µg/$585
Cancer Pathology
Cancer
Vimentin Mouse anti-Bovine Monoclonal (RV202) Antibody
Chicken, Bovine, Mouse, Goat, Dog, Rat, Hamster, Pig, Human, Monkey
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Vimentin Mouse anti-Human Monoclonal (33C7) Antibody
Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Vimentin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
Cancer Pathology
Cancer
Vimentin Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
Vimentin Mouse anti-Human Monoclonal (2A52) Antibody
Mouse, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
E. coli
6His, C-terminus
Less than 0.1 ng/µg of protein (less than 1EU/µg).
54.5 kDa
20 µg/$268; 100 µg/$349
E. coli
His
57.6 kD
100 µg/$420; 1 mg/$1,355; 20 µg/$323
Cancer Pathology
Vimentin Goat anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Cancer Pathology
Cancer
Vimentin Mouse anti-Human Monoclonal (AT5H8) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$460
Vimentin Mouse anti-Human Monoclonal Antibody
Chicken, Rat, Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$658
Vimentin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, WB
Unconjugated
100 µl/$299
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