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Catalog Number	Size	Price
LS-B4669-50	50 µl (0.5 mg/ml)	$460

Vimentin Antibody - Anti-Vimentin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Vimentin Antibody - Anti-Vimentin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Vimentin Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

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PathPlus™ Polyclonal Rabbit anti‑Human Vimentin Antibody (C‑Terminus, IHC, WB) LS‑B4669

Name: PathPlus™ Vimentin Polyclonal Antibody Rabbit anti-Human IHC,WB | LSBio
Brand: Lifespan BioSciences
SKU: LS-B4669-50
Price: 460.0000 USD
Availability: InStock
Rating: 5 (1 reviews)

Cancer Pathology Cancer

(5.0) Rating

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Note: This antibody replaces LS-C81189

Antibody:

Vimentin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Application:

IHC, IHC-P, WB

Reactivity:

Human

Format:

Unconjugated, Unmodified

Other formats:

Biotin FITC HRP

$460

LS-B4669-50

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

Vimentin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Application:

IHC, IHC-P, WB

Reactivity:

Human

Format:

Unconjugated, Unmodified

Other formats:

Biotin FITC HRP

Specifications

Description

Vimentin (VIM) is an intermediate filament component of the cytoskeleton of mesenchymal cells. It is important for maintaining cell integrity and shape. Vimentin also regulates cell migration via cytoskeletal rearrangements and is involved in regulating autophagy. In immunohistochemistry, it is positive in the cytoplasm of cells of mesenchymal origin, such as lymphocytes, endothelial cells, astrocytes, epidermal Langerhans cells, macrophages, and interstitial stromal cells. In cancer, it is positive in lymphomas and stromal tumors and is helpful for identifying melanomas, schwannomas and tumors of mesenchymal origin. References: Am J Surg Pathol. 2011;35:1722, PMID: 21997693; F1000Res. 2018 Nov 15;7. pii: F1000 Faculty Rev-1796, PMID: 30505430; PLoS One. 2019 Jan 30;14(1):e0209665, PMID: 30699149; Toxicol Pathol. 2010 Jan;38(1):131-41, PMID: 20028992

Target

Human Vimentin

Synonyms

VIM | Vimentin | vimenin

See All Vimentin Antibodies

Host

Rabbit

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG Polyclonal

Conjugations

Unconjugated. Also available conjugated with Biotin, FITC, HRP.

Purification

Immunoaffinity purified

Modifications

Unmodified

Immunogen

Synthetic peptide from C-Terminus of human VIM (P08670, NP_003371). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Dog, Bovine, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus (100%); Lizard, Xenopus (92%); Bat (86%); Stickleback (84%).

Epitope

C-Terminus

Specificity

Human VIM / Vimentin

Applications

IHC
IHC - Paraffin (5 µg/ml)
Western blot

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Usage

ELISA titer using peptide based assay: 1:62500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Presentation

PBS, 0.09% sodium azide, 2% sucrose

Storage

Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About Vimentin

Uniprot: P08670 NCBI: NM_003380 NP_003371.2

Validation

Anti-Vimentin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Anti-Vimentin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

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PathPlus™ Validation Process