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UCHL1 / PGP9.5
ubiquitin carboxyl-terminal hydrolase L1 (ubiquitin thiolesterase)
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
| Gene Name: | ubiquitin carboxyl-terminal hydrolase L1 (ubiquitin thiolesterase) |
| Family/Subfamily: | Protease , Cysteine C12 |
| Synonyms: | UCHL1, Ubiquitin C-terminal hydrolase, PARK5, PGP9.5, PGP95, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Uch-L1, Ubiquitin carboxyl-terminal esterase L1, HEL-117, NDGOA, HEL-S-53, SPG79 |
| Target Sequences: | NM_004181 NP_004172.2 P09936 |
Publications (4)
1
Optical clearing improves the imaging depth and signal-to-noise ratio for digital analysis and three-dimensional projection of the human enteric nervous system. Liu YA, Chen Y, Chiang AS, Peng SJ, Pasricha PJ, Tang SC. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2011 23:e446-57. (IHC)
[PubMed:21895876]
2
Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1. Zhang M, Deng Y, Luo Y, Zhang S, Zou H, Cai F, Wada K, Song W. Journal of neurochemistry. 2012 120:1129-38.
[PubMed:22212137]
3
The fetal ovary exhibits temporal sensitivity to a 'real-life' mixture of environmental chemicals. Lea RG, Amezaga MR, Loup B, Mandon-Pépin B, Stefansdottir A, Filis P, Kyle C, Zhang Z, Allen C, Purdie L, Jouneau L, Cotinot C, Rhind SM, Sinclair KD, Fowler PA. Scientific reports. 2016 6:22279. (WB; Human)
[Full Text Article]
[PubMed:26931299]
[PMC:PMC4773987]
Related Antibodies: LS-B489.
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Products
Antibodies
(184)
Type
Primary
(184)
Target
UCHL1 / PGP9.5
(184)
Reactivity
Human
(164)
Mouse
(93)
Rat
(85)
Bat
(8)
Bovine
(21)
Chimpanzee
(9)
Dog
(6)
Gibbon
(9)
Guinea pig
(19)
Hamster
(2)
Horse
(8)
Mammal
(1)
Monkey
(21)
Orangutan
(3)
Pig
(32)
Rabbit
(13)
Sheep
(4)
Zebrafish
(11)
Application
IHC
(80)
IHC-Fr
(5)
IHC-P
(46)
WB
(169)
Flo
(7)
ELISA
(63)
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(8)
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(24)
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(8)
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(4)
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(118)
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(60)
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(9)
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(4)
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(7)
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(44)
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(16)
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(23)
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(7)
IgG2a,k
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(2)
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(3)
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monoclonal mc
(58)
polyclonal pc
(124)
recombinant monoclonal rmc
(2)
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(2)
1B8-4D2
(1)
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(4)
346CT2.2.1
(6)
35
(1)
3D9
(1)
696CT2.1.4
(1)
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(2)
rUCHL1/775
(2)
SPM574
(2)
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(2)
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(3)
UCHL1/775
(3)
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(2)
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(2)
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(3)
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(7)
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(9)
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(16)
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(7)
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(3)
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(2)
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(2)
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(2)
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(14)
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(14)
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(9)
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(4)
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(112)
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aa2-223
(26)
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(9)
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(7)
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(7)
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(4)
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(2)
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(2)
31-80 aa, Internal
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Arg202
(1)
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(1)
aa100-150
(1)
aa100-200
(1)
aa120-153
(1)
aa150-C-term
(1)
aa171-220
(1)
aa200-223
(1)
aa58-68
(1)
Publications
No
(182)
Yes
(2)
UCHL1 / PGP9.5 Chicken anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
UCHL1 / PGP9.5 Goat anti-Human Polyclonal (aa58-68) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa100-200) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Cancer Pathology
Cancer
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (UMAB244) Antibody
Mouse, Rat, Human
IHC, PMA, WB
Unconjugated
100 µl/$493
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (Carrier-free) (UMAB244) Antibody
Mouse, Rat, Human
IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa200-223) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (BH7) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$376
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa187-214) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
Cancer Pathology
Cancer
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (1B8-4D2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$485
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Pig, Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa16-46) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa50-100) Antibody
Dog, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (31A3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.2 mg/$556
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal Antibody
Guinea pig, Rat, Pig, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$485
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa16-46) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa16-46) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Cancer Pathology
Cancer
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (OTI2B5) Antibody
Rat, Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
UCHL1 / PGP9.5 Mouse anti-Human Recombinant Monoclonal (rUCHL1/775) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
UCHL1 / PGP9.5 Mouse anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (rUCHL1/775) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, Carrier-free
100 µg/$574
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (13C4) Antibody
Zebrafish, Pig, Rat, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human
ELISA, IF, IHC, IHC-Fr, WB
Unconjugated
20 µg/$371; 100 µg/$574
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (13C4) Antibody
Zebrafish, Pig, Rat, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human
ELISA, IF, IHC, IHC-Fr, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Pig, Human, Monkey
IHC-P, WB
Unconjugated
50 µl/$460
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product results
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