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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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PODXL / Podocalyxin
podocalyxin-like
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
| Gene Name: | podocalyxin-like |
| Synonyms: | PODXL, GCTM-2 antigen, gp200, PCLP, PCLP-1, PCLP1, Podocalyxin-like protein 1, Podocalyxin, Podocalyxin-like, TRA-1-60, TRA-1-81 |
| Target Sequences: | NM_005397 NP_005388.2 O00592 |
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Antibodies
(88)
Type
Primary
(88)
Target
PODXL / Podocalyxin
(88)
Reactivity
Human
(72)
Mouse
(19)
Rat
(17)
Chimpanzee
(3)
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(3)
Hamster
(1)
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(1)
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(4)
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(9)
Application
IHC
(35)
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(23)
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(69)
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(20)
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(21)
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(1)
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(11)
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(4)
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(1)
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rabbit
(56)
mouse
(31)
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(1)
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(1)
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(1)
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(1)
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IgG
(24)
IgG1
(17)
IgG1,k
(1)
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(5)
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(1)
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(7)
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monoclonal mc
(31)
polyclonal pc
(57)
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(3)
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(3)
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(1)
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(3)
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(1)
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(3)
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(2)
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(2)
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(2)
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(2)
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(2)
PODXL/2185
(2)
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(1)
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(3)
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(4)
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(4)
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(8)
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(4)
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(3)
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(3)
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(3)
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(1)
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(1)
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(1)
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(8)
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(7)
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(6)
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(3)
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(46)
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(10)
aa153-386
(8)
aa171-404
(8)
aa220-463
(8)
aa410-439
(8)
aa32-461
(6)
Internal
(4)
aa131-180
(4)
aa301-350
(4)
C-Terminus
(1)
aa100-200
(1)
aa543-557
(1)
Publications
No
(88)
Cancer Pathology
Cancer
PODXL / Podocalyxin Mouse anti-Human Monoclonal (53D11) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
50 µg/$460
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) Antibody
Human
Flo, ICC, WB
Unconjugated
100 µg/$962
PODXL / Podocalyxin Mouse anti-Human Monoclonal (FITC) (53D11) Antibody
Human
Flo
FITC Conjugated
100 µl/$430
PODXL / Podocalyxin Mouse anti-Human Monoclonal (PE) (53D11) Antibody
Human
Flo
PE Conjugated
1 ml/$451
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
0.1 ml/$416
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (3D3) Antibody
Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (3D3) Antibody
Rabbit, Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (3D3) Antibody
Rabbit, Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PODXL / Podocalyxin Mouse anti-Human Monoclonal (SPM487) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$455
PODXL / Podocalyxin Goat anti-Human Polyclonal (aa543-557) Antibody
Rabbit, Mouse, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa410-439) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
PODXL / Podocalyxin Mouse anti-Human Monoclonal (4D2G7) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
50 µl/$316; 100 µl/$386
PODXL / Podocalyxin Mouse anti-Human Monoclonal (4H11) Antibody
Human
Flo, WB
Unconjugated
100 µg/$423
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa220-463) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
PODXL / Podocalyxin Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
PODXL / Podocalyxin Mouse anti-Human Monoclonal (5F5) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa131-180) Antibody
Human
WB
Unconjugated
100 µl/$397
PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa410-439) Antibody
Human
WB
Unconjugated
400 µl/$393
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
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of 88
product results
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