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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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OCLN / Occludin
occludin
OCLN / Occludin is an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination With Cell Polarization During Ameloblast Differentiation. Otsu K, Ida-Yonemochi H, Fujiwara N, Harada H. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2016 November;31:1943-1954. (Human)[Full Text Article]
[PubMed:27218883]
Related Antibodies: LS-B2320.
2
TLR3 deficiency exacerbates the loss of epithelial barrier function during genital tract Chlamydia muridarum infection. Kumar R, Gong H, Liu L, Ramos-Solis N, Seye CI, Derbigny WA. PloS one. 2019 January;14:e0207422. [Full Text Article]
[PubMed:30625140]
[PMC:PMC6326510]
Related Antibodies: LS-B2187.
3
Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1. Morgan Wong, Ashwinkumar Subramenium Ganapathy, Eric Suchanec, Laura Laidler, Thomas Ma, Prashant Nighot. American journal of physiology. Cell physiology. 2019 May;316:C753-C765. [Full Text Article]
[PubMed:30892937]
[PMC:PMC6580157]
Related Antibodies: LS-C140253.
4
Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland. Atsuko Y Higashi , Tomohito Higashi, Kyoko Furuse, Kana Ozeki, Mikio Furuse , Hideki Chiba. Scientific reports. 2021 Nov;11:21642. [Full Text Article]
[PubMed:34737342]
[PMC:PMC8568902]
Related Antibodies: LS-B2187.
5
TNF ?ARE Pigs: A Translational Crohn's Disease Model. Thomas Winogrodzki, Amira Metwaly, Alessandro Grodziecki, Wei Liang, Bernhard Klinger, Tatiana Flisikowska, Konrad Fischer, Krzysztof Flisikowski, Katja Steiger, Dirk Haller, Angelika Schnieke. Journal of Crohn's & colitis. 2023 July;17:1128-1138. [Full Text Article]
[PubMed:36821422]
[PMC:PMC10103242]
Related Antibodies: LS-B5737.
6
The tight-junction protein claudin-6 induces epithelial differentiation from mouse F9 and embryonic stem cells. Sugimoto K, Ichikawa-Tomikawa N, Satohisa S, Akashi Y, Kanai R, Saito T, Sawada N, Chiba H. PloS one. 2013 8:e75106. [Full Text Article]
[PubMed:24116027]
[PMC:PMC3792957]
Related Antibodies: LS-B2187.
7
ATF3 Protects Pulmonary Resident Cells from Acute and Ventilator-Induced Lung Injury by Preventing Nrf2 Degradation. Shan Y, Akram A, Amatullah H, Zhou DY, Gali PL, Maron-Gutierrez T, Gonz[Character e1]lez-L[Character f3]pez A, Zhou L, Rocco PR, Hwang D, Albaiceta GM, Haitsma JJ, Dos Santos CC. Antioxidants & redox signaling. 2014 Mar;22:651-68. [Full Text Article]
[PubMed:25401197]
[PMC:PMC4346377]
Related Antibodies: LS-B2187.
8
Protective role of uncoupling protein-2 against dextran sodium sulfate-induced colitis. Zhang H, Kuai XY, Yu P, Lin L, Shi R. Journal of gastroenterology and hepatology. 2012 Mar;27:603-8. [Full Text Article]
[PubMed:21871020]
Related Antibodies: LS-C50519.
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PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).