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Mouse IgG2a
The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. These domains shape the paratope — the antigen-binding site — at the amino terminal end of the monomer. The two variable domains bind the epitope on their specific antigens. In an experimental setting, Fc and Fab fragments can be generated in the laboratory. The enzyme papain can be used to cleave an immunoglobulin monomer into two Fab fragments and an Fc fragment. The enzyme pepsin cleaves below hinge region, so a F(ab')2 fragment and a pFc' fragment is formed. Recently another enzyme for generation of F(ab')2 has been commercially available. The enzyme IdeS (Immunoglobulin degrading enzyme from Streptococcus pyogenes, trade name FabRICATOR) cleaves IgG in a sequence specific manner at neutral pH. The F(ab')2 fragment can be split into two Fab' fragments by mild reduction.
Mouse IgG2a Target Details
| Target Name: | Mouse IgG2a |
Publications (2)
1
A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Barry MA, Wang Q, Jones KM, Heffernan MJ, Buhaya MH, Beaumier CM, Keegan BP, Zhan B, Dumonteil E, Bottazzi ME, Hotez PJ. Human vaccines & immunotherapeutics. 2016 April;12:976-87. (Mouse)
[Full Text Article]
[PubMed:26890466]
[PMC:PMC4962947]
Related Antibodies: LS-C59112.
2
Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. Junfei Wei, Leroy Versteeg, Zhuyun Liu, Brian Keegan, Ana Clara Gazzinelli-Guimarães, Ricardo T Fujiwara, Neima Briggs, Kathryn M Jones, Ulrich Strych, Coreen M Beaumier, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan. PLoS neglected tropical diseases. 2017 July;11:e0005769. [Full Text Article]
[PubMed:28708895]
[PMC:PMC5529013]
Related Antibodies: LS-C59112.
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Mouse IgG2a Goat anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC-Fr, IHC-P, WB
HRP Conjugated
1 ml/$356
Mouse IgG2a Goat anti-Mouse Polyclonal (FITC) Antibody
Mouse
Flo, IF, IHC, IHC-Fr
FITC Conjugated
0.5 mg/$338
Mouse IgG2a Rat anti-Mouse Monoclonal (LO-MG2a-7) Antibody
Mouse
ELISA
Unconjugated
250 µg/$725
Mouse IgG2a Rat anti-Mouse Monoclonal (HRP) Antibody
Mouse
ELISA
HRP Conjugated
500 µg/$860
Sandwich
96-Well Microplate
Mouse
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Mouse IgG2a Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
1 mg/$651
Mouse IgG2a Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA
Unconjugated
1 mg/$958
Mouse IgG2a Rat anti-Mouse Monoclonal (SB84a) Antibody
Mouse
ELISA, Flo, ICC, WB
Unconjugated
0.5 mg/$351
Mouse IgG2a Goat anti-Mouse Polyclonal (Atto 647N) Antibody
Mouse
FLISA, Flo, IF, WB
Atto 647N Conjugated
500 µg/$472
Mouse IgG2a Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
1 mg/$405
Mouse IgG2a Mouse anti-Mouse Monoclonal (HOPC-1) Antibody
Mouse
Flo, ICC, IHC, IP
Unconjugated
50 µg/$347
Mouse IgG2a Rat anti-Mouse Monoclonal (Biotin) (SB84a) Antibody
Mouse
ELISA, Flo, ICC, WB
Biotin Conjugated
0.5 mg/$374
Mouse IgG2a Goat anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IF, IHC, WB
HRP Conjugated
100 µl/$496
Mouse IgG2a Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, ID, IHC, IP, WB
Unconjugated
1 mg/$575
Mouse IgG2a Goat anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, Flo, IHC, WB
Biotin Conjugated
1 mg/$391
Mouse IgG2a Goat anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, ICC, IHC, WB
HRP Conjugated
1 mg/$396
Mouse IgG2a Goat anti-Mouse Polyclonal (AP) Antibody
Mouse
ELISA, ICC, IHC, WB
AP Conjugated
0.5 mg/$370
Mouse IgG2a Goat anti-Mouse Polyclonal (TR) Antibody
Mouse
DB, FLISA, IF, IHC, WB
TR Conjugated
1 mg/$368
Mouse IgG2a Goat anti-Mouse Polyclonal (Atto 425) Antibody
Mouse
FLISA, Flo, IF, WB
Atto 425 Conjugated
500 µg/$472
Mouse IgG2a Rabbit anti-Mouse Polyclonal (AP) Antibody
Mouse
ELISA, IHC, WB
AP Conjugated
1 mg/$417
Mouse IgG2a Mouse anti-Mouse Monoclonal (PE) Antibody
Mouse
ICC, IP, WB
PE Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112; 2 ml/$1,495; 5 ml/$2,801
Mouse IgG2a Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Human
Flo, IF
FITC Conjugated
1 mg/$603
Mouse IgG2a Goat anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
1 mg/$376
Mouse IgG2a Rat anti-Mouse Monoclonal (Concentrated) (LO-MG2a-2) Antibody
Mouse
IHC, IHC-Fr
Unconjugated, Concentrated
1 ml/$824
Mouse IgG2a Rat anti-Mouse Monoclonal (PE) (SB84a) Antibody
Mouse
FLISA, Flo
PE Conjugated
0.1 mg/$369
Viewing 1-25
of 142
product results
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