LIG4 / DNA Ligase IV

ligase IV, DNA, ATP-dependent

LIG4 / DNA Ligase IV is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.

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Products

Antibodies (24)

Type

Primary (24)

Target

LIG4 / DNA Ligase IV (24)

Reactivity

Human (24)

Mouse (4)

Rat (1)

Bovine (1)

Dog (1)

Gibbon (3)

Horse (3)

Monkey (3)

Orangutan (3)

Application

IHC (18)

IHC-P (6)

WB (15)

ELISA (9)

ICC (1)

IF (6)

Peptide-ELISA (5)

Host

rabbit (23)

mouse (1)

Isotype

IgG (19)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (23)

Clone

1A4 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (21)

Epitope

aa275-324 (4)

590-670 aa (2)

Internal (2)

560-640 aa, Internal (1)

Ab-650 (1)

Gly619 (1)

aa239-267 (1)

aa591-640 (1)

aa616-665 (1)

pThr650 (1)

Publications

No (24)

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LIG4 / DNA Ligase IV Antibody (aa275-324) LS-C31455

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa275-324) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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LIG4 / DNA Ligase IV Antibody (aa275-324, HRP) LS-C430583

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa275-324) (HRP) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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LIG4 / DNA Ligase IV Antibody (aa275-324, Biotin) LS-C430581

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa275-324) (Biotin) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

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LIG4 / DNA Ligase IV Antibody (aa275-324, FITC) LS-C430582

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa275-324) (FITC) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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LIG4 / DNA Ligase IV Antibody (560-640 aa, Internal) LS-C383151

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (560-640 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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LIG4 / DNA Ligase IV Antibody (590-670 aa) LS-C381605

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (590-670 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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LIG4 / DNA Ligase IV Antibody LS-C331665

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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LIG4 / DNA Ligase IV Antibody (Internal) LS-C352452

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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LIG4 / DNA Ligase IV Antibody LS-C809559

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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LIG4 / DNA Ligase IV Antibody (Gly619) LS-C176883

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (Gly619) Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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LIG4 / DNA Ligase IV Antibody LS-C752446

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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LIG4 / DNA Ligase IV Antibody LS-C804697

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

LIG4 / DNA Ligase IV Antibody (Internal) LS-C413211

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$321

Select

LIG4 / DNA Ligase IV Antibody (590-670 aa) LS-C383149

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (590-670 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LIG4 / DNA Ligase IV Antibody (Ab-650) LS-C823333

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (Ab-650) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

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LIG4 / DNA Ligase IV Antibody LS-C832144

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

LIG4 / DNA Ligase IV Antibody LS-C830636

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

LIG4 / DNA Ligase IV Antibody (aa616-665) LS-C291228

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa616-665) Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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LIG4 / DNA Ligase IV Antibody (phospho-Thr650) LS-C291176

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (pThr650) Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

LIG4 / DNA Ligase IV Antibody LS-C823592

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

LIG4 / DNA Ligase IV Antibody (aa591-640) LS-C119547

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa591-640) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

LIG4 / DNA Ligase IV Antibody LS-C833994

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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LIG4 / DNA Ligase IV Antibody (clone 1A4) LS-C197616

Antibody:

LIG4 / DNA Ligase IV Mouse anti-Human Monoclonal (1A4) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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LIG4 / DNA Ligase IV Antibody (aa239-267) LS-C203791

Antibody:

LIG4 / DNA Ligase IV Rabbit anti-Human Polyclonal (aa239-267) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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