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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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ITGA5/Integrin Alpha 5/CD49e
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA5/Integrin Alpha 5/CD49e belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.
| Gene Name: | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGA5, FNRA, Integrin alpha-5, Integrin Alpha 5, Integrin alpha-F, VLA-5, CD49e, CD49e antigen, VLA5A |
| Target Sequences: | NM_002205 NP_002196.2 P08648 |
Publications (3)
1
Correction to: In vivo imaging of early stages of rheumatoid arthritis by a5ß1-integrin-targeted positron emission tomography. Notni J, Gassert FT, Steiger K, Sommer P, Weichert W, Rummeny EJ, Schwaiger M, Kessler H, Meier R, Kimm MA. EJNMMI research. 2019 December;9:107. [Full Text Article]
[PubMed:31828445]
[PMC:PMC6906272]
Related Antibodies: LS-B6179.
2
Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker a5ß1 Integrin. Zhao-Hui Jin, Takako Furukawa, Katsushi Kumata, Lin Xie, Joji Yui, Hidekatsu Wakizaka, Yasuhisa Fujibayashi, Ming-Rong Zhang, Tsuneo Saga. Biological & pharmaceutical bulletin. 2015 August;38:1722-31. [Full Text Article]
[PubMed:26277991]
3
Complementary, Selective PET Imaging of Integrin Subtypes a5ß1 and avß3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin. Johannes Notni, Katja Steiger, Frauke Hoffmann, Dominik Reich, Tobias G Kapp, Florian Rechenmacher, Stefanie Neubauer, Horst Kessler, Hans-Jürgen Wester. The Breast : official journal of the European Society of Mastology. 2016 Mar;;57:460-6. [Full Text Article]
[PubMed:26635338]
Related Antibodies: LS-B6179.
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Products
Antibodies
(104)
Proteins
(8)
ELISA Kits
(5)
Type
Custom
(1)
Over-Expression Lysate
(2)
Primary
(104)
Recombinant
(6)
Sandwich
(4)
Target
ITGA5/Integrin Alpha 5/CD49e
(117)
Reactivity
Human
(79)
Mouse
(47)
Rat
(15)
Bovine
(9)
Chicken
(1)
Chimpanzee
(3)
Cow
(8)
Dog
(5)
Gibbon
(3)
Hamster
(1)
Orangutan
(3)
Application
IHC
(32)
IHC-Fr
(12)
IHC-P
(5)
WB
(71)
Flo
(33)
DB
(5)
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(26)
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rabbit
(69)
mouse
(23)
hamster
(2)
rat
(10)
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(2)
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(36)
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(1)
IgG2a
(9)
IgG2a,k
(6)
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(4)
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(6)
Clonality
monoclonal mc
(35)
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(69)
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05
(1)
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(12)
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(9)
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(1)
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(9)
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(1)
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(51)
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aa649-900
(8)
aa895-1049
(8)
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aa787-992
(1)
aa796-824
(1)
aa876-925
(1)
heavy chain, Cleaved-Phe42
(1)
light chain, Cleaved-Glu895
(1)
Publications
No
(116)
Yes
(1)
Sample Type
Cell Lysates
(1)
Plasma
(3)
Serum
(3)
Tissue Homogenates
(2)
Tag
6His, C-terminus
(2)
His-GST
(3)
Myc-DDK (Flag)
(3)
Species
Bovine
(1)
Human
(5)
Mouse
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(2)
Human Cells
(1)
Mammalian Cells
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(2)
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Rat, Hamster, Mouse, Human
ELISA, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$485
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal (10F6) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal (561-610 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (Biotin) (MFR5) Antibody
Mouse
Flo, IHC, IHC-Fr
Biotin Conjugated
500 µg/$548
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Cow Polyclonal (aa649-900) Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,393
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal (aa575-602) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (FITC) (5H10.27) Antibody
Mouse
Flo, IHC, IHC-Fr
FITC Conjugated
0.5 mg/$462
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ITGA5/Integrin Alpha 5/CD49e Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal (NKI-SAM-1) Antibody
Human
Flo, ICC, IHC, IP
Unconjugated
0.1 mg/$424
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal Antibody
Dog, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
200 µg/$677
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal (10F6) Antibody
Human
Flo, IHC, WB
Unconjugated
100 µl/$541
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal (6F6C1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
ITGA5/Integrin Alpha 5/CD49e Mouse anti-Human Monoclonal (8D1G12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (Azide-free) (MFR5) Antibody
Mouse
Flo, IHC, IHC-Fr
Unconjugated, Azide-free
500 µg/$568
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (MFR5) Antibody
Mouse
Flo, IHC, IHC-Fr
Unconjugated
500 µg/$517
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (5H10.27) Antibody
Mouse
Flo, IHC, IHC-Fr
Unconjugated
0.5 mg/$398
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (5H10.27) Antibody
Mouse
Flo, IHC, IHC-Fr
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$435
ITGA5/Integrin Alpha 5/CD49e Rat anti-Mouse Monoclonal (G1/G1-4) Antibody
Mouse
Flo, IHC
Unconjugated
50 µg/$444
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product results
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