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FN1 / Fibronectin
fibronectin 1
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
| Gene Name: | fibronectin 1 |
| Synonyms: | FN1, CIG, Cold-insoluble globulin, Fibronectin 1, FINC, LETS, GFND, ED-B, Fibronectin, FN, FNZ, GFND2, Migration-stimulating factor, MSF |
| Target Sequences: | NM_002026 NP_002017.1 P02751 |
Publications (5)
1
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes. Xinlei Li, Ruju Chen, Sherri Kemper, David R Brigstock. Frontiers in cell and developmental biology. 2021 Mar;9:640667. [Full Text Article]
[PubMed:33816490]
[PMC:PMC8012540]
2
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart. Árpád Kovács , Melissa Herwig , Heidi Budde , Simin Delalat , Detmar Kolijn , Beáta Bódi, Roua Hassoun , Melina Tangos , Saltanat Zhazykbayeva , Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S Dhalla, Andreas Mügge , Attila Tóth , Zoltán Papp , Judit Barta, Nazha Hamdani. Antioxidants. 2021 Jun;10:964. [Full Text Article]
[PubMed:34208541]
[PMC:PMC8234177]
3
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Edwin K Jackson, Zaichuan Mi, Delbert G Gillespie, Dongmei Cheng, Stevan P Tofovic. Journal of the American Heart Association. 2021 March;10:e020088. [Full Text Article]
[PubMed:33682436]
[PMC:PMC8174220]
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(196)
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FN1 / Fibronectin
(196)
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(149)
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(56)
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(34)
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(9)
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(3)
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(3)
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(8)
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(3)
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(7)
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(20)
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(2)
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(77)
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(14)
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(40)
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(147)
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(68)
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(11)
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(5)
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(23)
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(5)
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(3)
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(7)
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(7)
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(18)
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(17)
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(11)
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(5)
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(97)
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aa1998-2106
(8)
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(8)
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(8)
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(8)
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(6)
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(6)
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(4)
ED-B domain of fibronectin
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2310-2390 aa, C-terminal
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Phe2372
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(1)
Publications
No
(196)
FN1 / Fibronectin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$515
FN1 / Fibronectin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$525
FN1 / Fibronectin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
FN1 / Fibronectin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
1 mg/$594
FN1 / Fibronectin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
FN1 / Fibronectin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
FN1 / Fibronectin Mouse anti-Human Monoclonal (aa1965-2176) (2F4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
FN1 / Fibronectin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$594; 1 mg/$3,527
FN1 / Fibronectin Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Bovine, Rat, Human, Monkey
ELISA, IHC, IP, WB
Biotin Conjugated
100 µg/$559
FN1 / Fibronectin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Biotin Conjugated
100 µg/$878
FN1 / Fibronectin Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$930
FN1 / Fibronectin Mouse anti-Human Monoclonal (B476) Antibody
Human
IHC, IHC-Fr
Unconjugated
0.5 ml/$328
FN1 / Fibronectin Mouse anti-Human Monoclonal (2F4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
FN1 / Fibronectin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
50 µg/$460
FN1 / Fibronectin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (568) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
FN1 / Fibronectin Mouse anti-Human Monoclonal (HFN7.1) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
FN1 / Fibronectin Mouse anti-Human Monoclonal (aa32-307) (OTI1G2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
FN1 / Fibronectin Mouse anti-Human Monoclonal Antibody
Mouse, Human
IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$466
FN1 / Fibronectin Mouse anti-Human Monoclonal (875A51) Antibody
Human
ELISA, IHC-Fr, WB
Unconjugated
0.5 mg/$873
FN1 / Fibronectin Mouse anti-Human Monoclonal (aa32-307) (Carrier-free) (OTI5C1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FN1 / Fibronectin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$440; 1 mg/$594; 10 mg/$3,447
FN1 / Fibronectin Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µg/$449; 1 mg/$614; 10 mg/$3,612
FN1 / Fibronectin Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
1 mg/$665; 10 mg/$3,612
FN1 / Fibronectin Rabbit anti-Cow Polyclonal Antibody
Bovine, Cow
ICC, IP, WB
Unconjugated
100 µl/$274; 200 µl/$301; 500 µl/$391; 1 ml/$437; 2 ml/$527; 5 ml/$889
FN1 / Fibronectin Rabbit anti-Cow Polyclonal (Biotin) Antibody
Bovine, Cow
ICC, IP, WB
Biotin Conjugated
100 µl/$280; 200 µl/$310; 500 µl/$409; 1 ml/$459; 2 ml/$558; 5 ml/$956
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