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Complement component 3 (C3) is a protein that is central to activating the complement system and it plays a role in the innate immune system. C3c is a stable C3 conversion product, and it is the major fragment resulting from the C3 cleavage by C3 convertase and Factor i. It is composed of an intact beta chain bound to two fragments of the alpha chain. Expression levels of C3c in patients with stable systolic heart failure are associated positively with survival (PMID 24489446).
Target Name: | Complement C3 / C3c |
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