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Newark, CA 94560
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AIRE

autoimmune regulator

The AIRE gene function is not well defined, however the protein does contain zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described [1]. The longer AIRE-1 mRNA appears to be more abundant and includes exons 1 through 14. Splice variant AIRE-2 includes a portion of the non-coding region of exon 1, an alternatively spliced longer exon 8, plus exons 9 through 14. Variant AIRE-3 includes the same exon 1-8-9 sequences as found in AIRE-2 but utilizes additional alternative splicing in exon 10 that shifts the reading frame such that a stop codon in exon 12 is utilized. The resulting protein products of these splice variants are differ significantly. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Gene Name: autoimmune regulator
Synonyms: AIRE, APSI, AIRE1, Autoimmune regulator, APECED, APS1, APECED protein, PGA1
Target Sequences: NM_000383 NP_000374.1 O43918

☰ Filters
Antibodies (59)
ELISA Kits (16)
Proteins (5)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Competitive EIA (1)
Custom (1)
Over-Expression Lysate (4)
Primary (59)
Recombinant (1)
Sandwich (11)
Sandwich CLIA (1)
AIRE (80)
Human (66)
Mouse (28)
Rat (10)
Bovine (6)
Chicken (1)
Chimpanzee (6)
Dog (4)
Guinea pig (7)
Hamster (1)
Horse (13)
Monkey (13)
Porcine (1)
Rabbit (1)
IHC (14)
IHC-P (8)
WB (55)
Flo (2)
ELISA (18)
ICC (8)
IF (18)
Peptide-ELISA (6)
rabbit (52)
goat (5)
rabbit-new zealand white (2)
Product Group
IHCPlus (4)
IgG (42)
polyclonal pc (59)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (12)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (1)
Unconjugated (36)
aa76-125 (8)
aa64-92 (7)
N-Terminus (4)
aa218-267 (4)
aa467-516 (4)
100-180 aa (2)
pSer156 (2)
60-140 aa, Internal (1)
Internal (1)
Pro126 (1)
aa100-150 (1)
aa102-115 (1)
aa126-175 (1)
aa159-172 (1)
aa30-80 (1)
aa476-545 (1)
aa476-552 (1)
aa534-545 (1)
aa91-140 (1)
p156 (1)
No (79)
Yes (1)
Adherent Cell Cultures (2)
Plasma (6)
Serum (6)
Tissue Homogenates (3)
Myc-DDK (Flag) (5)
Human (3)
293T Cells (2)
HEK 293 Cells (3)
AIRE Antibody - Anti-AIRE antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
AIRE Goat anti-Human Polyclonal (aa534-545) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIRE Antibody - Anti-AIRE antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AIRE Goat anti-Human Polyclonal (aa102-115) Antibody
Dog, Rat, Hamster, Horse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIRE Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AIRE Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
AIRE Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AIRE Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
AIRE Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AIRE Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
AIRE Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AIRE Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
AIRE Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AIRE Antibody - Western blot - Anti-AIRE/Aire 1 Picoband Antibody
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
AIRE Antibody - Paraffin-embedding Immunohistochemistry using human pancreatic tissue at dilution 1:100
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AIRE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
AIRE ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
AIRE Antibody - Western blot of HeLa cell lysate using AIRE Antibody
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
AIRE Antibody - Immunofluorescent analysis of AIRE staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Select
AIRE Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
200 µl/$734
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) (Biotin) Antibody
Mouse, Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) (FITC) Antibody
Mouse, Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) (APC) Antibody
Mouse, Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) (PE) Antibody
Mouse, Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
AIRE Antibody - Western blot of AIRE-1 antibody
Select
AIRE Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
AIRE Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using AIRE antibody.
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
AIRE Antibody - Immunofluorescence analysis of HeLa cells, using AIRE Antibody. The picture on the right is blocked with the synthesized peptide.
Select
AIRE Rabbit anti-Human Polyclonal (aa91-140) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
AIRE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
AIRE Antibody - AIRE Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The AIRE antibody detected the AIRE protein (arrow).
Select
AIRE Rabbit anti-Human Polyclonal (aa64-92) Antibody
Mouse, Human
IF, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 80 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).