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| Catalog Number | Size | Price |
|---|---|---|
| LS-C751150-100 | 100 µg (1 mg/ml) | $574 |
1 of 2
2 of 2
Recombinant Monoclonal Rabbit anti‑Human PLAP / Alkaline Phosphatase Antibody (clone ALPP/2899R, Azide‑free,Carrier‑free, IHC) LS‑C751150
Recombinant Monoclonal Rabbit anti‑Human PLAP / Alkaline Phosphatase Antibody (clone ALPP/2899R, Azide‑free,Carrier‑free, IHC) LS‑C751150
Antibody:
PLAP / Alkaline Phosphatase Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (ALPP/2899R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
PLAP / Alkaline Phosphatase Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (ALPP/2899R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Specifications
Description
Alkaline Phosphatase antibody LS-C751150 is an unconjugated rabbit recombinant monoclonal antibody to human Alkaline Phosphatase (PLAP). Validated for IHC.
Target
Human PLAP / Alkaline Phosphatase
Synonyms
ALPP | ALP | Alkaline phosphomonoesterase | Glycerophosphatase | PALP | PLAP | PLAP-1 | Alp1 | Germ-cell alkaline phosphatase | Nagao isozyme | Regan isozyme
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Clone
ALPP/2899R
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available Unmodified.
Immunogen
Recombinant full-length human ALPP protein. Antigen Molecular Weight: 70 kDa
Specificity
Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
Applications
- IHC - Paraffin (0.25 - 0.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistology (Formalin-fixed - 0.25-0.5 ug/ml for 30 minutes at RT - No special pretreatment is required for the immunohistochemical staining of formalin-fixed tissues.. Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PLAP / Alkaline Phosphatase
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Featured Products
Species:
Human
Applications:
IHC, IHC - Frozen, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, ELISA
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Human
Applications:
Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/23/2024
Date Requested: 12/23/2024
