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Catalog Number Size Price
LS-C44264-0.2 0.2 mg $486 
Antibody

Monoclonal Mouse anti‑Human PLAP / Alkaline Phosphatase Antibody (clone H17E2, IHC) LS‑C44264

Monoclonal Mouse anti‑Human PLAP / Alkaline Phosphatase Antibody (clone H17E2, IHC) LS‑C44264

Antibody:
PLAP / Alkaline Phosphatase Mouse anti-Human Monoclonal (H17E2) Antibody
Application:
IHC, IHC-Fr, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$486
LS-C44264-0.2
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
PLAP / Alkaline Phosphatase Mouse anti-Human Monoclonal (H17E2) Antibody
Application:
IHC, IHC-Fr, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Alkaline Phosphatase antibody LS-C44264 is an unconjugated mouse monoclonal antibody to human Alkaline Phosphatase (PLAP). Validated for ELISA, Flow and IHC. Cited in 4 publications.
Target
Human PLAP / Alkaline Phosphatase
Synonyms
ALPP | ALP | Alkaline phosphomonoesterase | Glycerophosphatase | PALP | PLAP | PLAP-1 | Alp1 | Germ-cell alkaline phosphatase | Nagao isozyme | Regan isozyme
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
H17E2
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Placental membrane.
Specificity
Recognizes human placental alkaline phosphate, a 67kD isoform expressed in trophoblast cells of normal human placenta, in seminomas and in ovarian carcinoma. The H17E2 antibody has been widely used in immunolocalization studies of germ cell tumors and may also be used in ELISA based assays for the measurement of soluble PLAP.
Applications
  • IHC
  • IHC - Frozen
  • Flow Cytometry (10 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Presentation
PBS, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PLAP / Alkaline Phosphatase
P05187 NM_001632 NP_001623.3

LSBio Ratings

PLAP / Alkaline Phosphatase Antibody (clone H17E2) for IHC, Flow, ELISA LS-C44264 has an LSBio Rating of
Publications (4.3)

Publications (4)

Fusion of Epstein-Barr virus with epithelial cells can be triggered by v5 in addition to v6 and v8, and integrin binding triggers a conformational change in glycoproteins gHgL. Chesnokova LS, Hutt-Fletcher LM. Journal of virology. 2011 85:13214-23. (Human)

alpha v beta 3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1. Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G. Proceedings of the National Academy of Sciences of the United States of America. 2012 Nov;109:19792-7.

alpha v beta 6- and alpha v beta 8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion. Gianni T, Salvioli S, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G. PLoS pathogens. 2013 Dec;9:e1003806.

Duration of simulated microgravity affects the differentiation of mesenchymal stem cells. Xue L, Li Y, Chen J. Molecular medicine reports. 2017 15:3011-3018. (Flo; Human)

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Requested From: United States
Date Requested: 11/22/2024