Human IL-33

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Biotin. Also available Unconjugated or conjugated with FITC, HRP.

Protein G purified

Unmodified

Recombinant human Interleukin-33 protein (123-276AA)

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).

• ELISA
• Applications tested for the base form of this product only

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.

Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: O95760 NCBI: NM_033439 NP_254274.1