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TRPC6

transient receptor potential cation channel, subfamily C, member 6

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.

Gene Name: transient receptor potential cation channel, subfamily C, member 6
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPC6, Transient receptor protein 6, Trrp6, TRP-6, TRP6, FSGS2
Target Sequences: NM_004621 NP_004612.2 Q9Y210

Publications (1)

1
Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels. Azmi A Ahmad, Molly E Streiff, Chris Hunter, Frank B Sachse. Frontiers in physiology. 2020 Feb;11:44. [Full Text Article] [PubMed:32116757] [PMC:PMC7033547] Related Antibodies: LS-C19628.

☰ Filters
Antibodies (35)
Proteins (2)
ELISA Kits (1)
Primary (35)
Recombinant (2)
Sandwich (1)
TRPC6 (38)
Human (34)
Mouse (15)
Rat (13)
Chimpanzee (4)
Gibbon (3)
Horse (3)
Pig (13)
Rabbit (3)
Zebrafish (1)
IHC (10)
IHC-P (4)
WB (31)
Flo (1)
ELISA (6)
IF (4)
IP (1)
Peptide-ELISA (3)
rabbit (31)
mouse (1)
goat (3)
Product Group
IHCPlus (3)
IgG (12)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (34)
3F2.H10.F2 (1)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (22)
aa1-192 (8)
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aa792-841 (4)
aa10-60 (1)
aa249-265 (1)
aa350-400 (1)
aa832-846 (1)
aa918-930 (1)
aa918-931 (1)
No (37)
Yes (1)
Cell Lysates (1)
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GST, N-terminus (1)
His-S (1)
Human (2)
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Wheat Germ Extract (1)
TRPC6 Antibody - Immunohistochemistry of TRPC6 in mouse lung tissue with TRPC6 antibody at 10 ug/ml.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
TRPC6 Antibody - Anti-TRPC6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
TRPC6 Antibody - TRPC6 antibody. IHC(P): Human Intestinal Cancer Tissue.
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TRPC6 Rabbit anti-Human Polyclonal (aa249-265) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TRPC6 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TRPC6 Goat anti-Mouse Polyclonal (aa832-846) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$460
TRPC6 Antibody - Western blot analysis of extract of various cells.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
TRPC6 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
TRPC6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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TRPC6 Rabbit anti-Zebrafish Polyclonal Antibody
Zebrafish
IHC, WB
Unconjugated
500 µg/$393
TRPC6 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TRPC6 Rabbit anti-Human Polyclonal (aa350-400) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
TRPC6 Antibody - TRPC6 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRPC6 Rabbit anti-Human Polyclonal (aa792-841) Antibody
Rat, Human
WB
Unconjugated
100 µl/$424
TRPC6 Antibody - TRPC6 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRPC6 Rabbit anti-Human Polyclonal (aa792-841) (Biotin) Antibody
Mouse, Rat, Pig, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
TRPC6 Antibody - TRPC6 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRPC6 Rabbit anti-Human Polyclonal (aa792-841) (FITC) Antibody
Mouse, Rat, Pig, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
TRPC6 Antibody - TRPC6 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRPC6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
TRPC6 Antibody - Immunohistochemistry using the anti-TRPC6 monoclonal antibody shows detection of TRPC6 in human adrenal (cortex) tissue (40X). The antibody was used a dilution to 2.5 µg/mL. The image shows strong staining with minimal background staining. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain.
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TRPC6 Mouse anti-Human Monoclonal (3F2.H10.F2) Antibody
Human, Chimpanzee
ELISA, IHC, WB
Unconjugated
25 µl/$304
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
TRPC6 Antibody - Immunofluorescence analysis of HeLa cells using TRPC6 antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
TRPC6 Antibody - Goat Anti-TRPC6 Antibody (1µg/ml) staining of A549 cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescencence.
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TRPC6 Goat anti-Human Polyclonal (aa918-930) Antibody
Pig, Human
Flo, Peptide-ELISA, WB
Unconjugated
100 µg/$503
TRPC6 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using TRPC6 Polyclonal Antibody at dilution of 1:50.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TRPC6 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using TRPC6 Polyclonal Antibody at dilution of 1:40.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TRPC6 Antibody - Immunofluorescence analysis of HeLa cells using TRPC6 Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TRPC6 Antibody - TRPC6 antibody (0.03 ug/ml) staining of Human Placenta lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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TRPC6 Goat anti-Human Polyclonal (aa918-931) Antibody
Pig, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$461
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TRPC6 Antibody
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
TRPC6 Antibody - Western blot analysis of TRPC6 using anti-TRPC6 antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat ovary tissue lysate,Lane 2: mouse lung tissue lysate. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-TRPC6 antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for TRPC6 at approximately 106KD. The expected band size for TRPC6 is at 106KD.
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TRPC6 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
TRPC6 Antibody - Western blot of TRPC6 antibody with the recombinant protein used as the immunogen.
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TRPC6 Rabbit anti-Human Polyclonal (aa1-192) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 38 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).