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TNFRSF11A / RANK
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11A / RANK is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
| Gene Name: | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| Family/Subfamily: | TNF Receptor , not assigned-TNF Receptor |
| Synonyms: | TNFRSF11A, CD265, CD265 antigen, ODFR, LOH18CR1, OPTB7, OSTS, PDB2, RANK, Receptor activator of NF-KB, TRANCER, FEO, OFE |
| Target Sequences: | NM_003839 NP_003830.1 Q9Y6Q6 |
Publications (2)
1
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation. Yugo Morita, Motoo Saito, Javier Rangel-Moreno, Anthony M Franchini, John R Owen, John C Martinez, John L Daiss, Karen L de Mesy Bentley, Stephen L Kates, Edward M Schwarz, Gowrishankar Muthukrishnan. Bone research. 2022 August;10:56. [Full Text Article]
[PubMed:36028492]
[PMC:PMC9418173]
Related Antibodies: LS-B2077.
2
Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis. Peggy Perrin, Jérome Olagne, Arnaud Delbello, Stanislas Bataille, Laurent Mesnard, Claire Borni, Bruno Moulin, Sophie Caillard. Kidney international reports. 2022 February;7:343-349. [Full Text Article]
[PubMed:35155875]
[PMC:PMC8820998]
Related Antibodies: LS-B11252.
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Antibodies
(78)
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(78)
Target
TNFRSF11A / RANK
(78)
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(60)
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(27)
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(61)
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(13)
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(12)
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(58)
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(20)
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(58)
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(2)
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(2)
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(7)
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(4)
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(4)
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(6)
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(6)
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(38)
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(1)
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(1)
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(1)
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(1)
Publications
No
(76)
Yes
(2)
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa603-613) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (9A725) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (Azide-free) (9A725) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa33-208) (Azide-free) (64C1385.1) Antibody
Mouse, Human
Flo, IP, WB
Unconjugated, Azide-free
0.1 mg/$386
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa60-120) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (PE) Antibody
Human
Flo
PE Conjugated
100 µl/$836
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa450-500) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$657
TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (PE) (9A725) Antibody
Mouse, Human
Flo
PE Conjugated
0.1 ml/$416
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, WB
Unconjugated, Preservative Free
100 µl/$412
TNFRSF11A / RANK Mouse anti-Human Monoclonal (8H8B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
TNFRSF11A / RANK Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IP
Unconjugated
250 µg/$732
TNFRSF11A / RANK Rat anti-Mouse Monoclonal (HRP) Antibody
Mouse
ELISA, Flo, IP
HRP Conjugated
100 µl/$951
TNFRSF11A / RANK Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
ELISA, Flo, IP
FITC Conjugated
100 µl/$951
TNFRSF11A / RANK Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
ELISA, Flo, IP
PE Conjugated
100 µl/$951
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa330-615) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
TNFRSF11A / RANK Mouse anti-Human Monoclonal (Extracellular Domain) (64C1385.1) Antibody
Mouse, Human
Flo, IP, WB
Unconjugated
0.1 mg/$386
TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa29-44) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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product results
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