Human TNFRSF11A / RANK

Rabbit

Human (tested or 100% immunogen sequence identity)

Monkey (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

A synthetic peptide corresponding to a sequence at the N-Terminus of human RANK (29-44 aa QIAPPCTSEKHYEHLG). Percent identity by BLAST analysis: Human, Gorilla (100%); Baboon, Monkey (94%); Gibbon (88%); Orangutan, Marmoset (81%); Rat (69%).

aa29-44

Human TNFRSF11A / RANK

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)

Receptor Activator of Nuclear Factor K B, also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL (Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al.(1997) mapped the RANK gene to 18q22.1.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9Y6Q6 NCBI: NM_003839 NP_003830.1