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TLR9
toll-like receptor 9
TLR9 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
| Gene Name: | toll-like receptor 9 |
| Family/Subfamily: | Toll-like Receptor , not assigned-Toll-like Receptor |
| Synonyms: | TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9 |
| Target Sequences: | NM_017442 NP_059138.1 Q9NR96 |
Publications (1)
1
Association of self-DNA mediated TLR9-related gene, DNA methyltransferase, and cytokeratin protein expression alterations in HT29-cells to DNA fragment length and methylation status. Fűri I, Sipos F, Spisák S, Kiszner G, Wichmann B, Schöller A, Tulassay Z, Műzes G, Molnár B. TheScientificWorldJournal. 2014 2013:293296. (WB; Human)
[Full Text Article]
[PubMed:24459426]
[PMC:PMC3891537]
Related Antibodies: LS-B2341.
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TLR9 Mouse anti-Human Monoclonal (aa268-284) (26C593.2) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
TLR9 Mouse anti-Human Monoclonal (aa268-284) (FITC) Antibody
Mouse, Dog, Rat, Horse, Human, Monkey
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
FITC Conjugated
50 µg/$485
TLR9 Goat anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse, Hamster
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$515
TLR9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
TLR9 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
TLR9 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
TLR9 Mouse anti-Human Monoclonal (aa1-815) (FITC) (5G5) Antibody
Mouse, Dog, Human
Flo, IHC, IHC-Fr, IHC-P, WB
FITC Conjugated
100 µg/$617
E. coli
His-GST, N-terminus
94.1 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
E. coli
6His, N-terminus
41.2 kDa
50 µg/$422; 10 µg/$278; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TLR9 Mouse anti-Human Monoclonal (aa1-815) Antibody
Mouse, Dog, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$554; 250 µg/$1,025
TLR9 Mouse anti-Human Monoclonal (3G7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
TLR9 Mouse anti-Human Monoclonal (1B12H2) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
TLR9 Mouse anti-Human Monoclonal (aa268-284) (Azide-free) (11E377) Antibody
Mouse, Dog, Rat, Rhesus monkey, Human, Monkey
Flo, ICC, IHC, WB
Unconjugated, Azide-free
100 µg/$763
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
TLR9 Mouse anti-Human Monoclonal (Concentrated) (Biotin) (5G5) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, WB
Biotin Conjugated, Concentrated
1 ml/$473
TLR9 Mouse anti-Human Monoclonal (5B10E8) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
TLR9 Mouse anti-Human Monoclonal (6B2G1) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
TLR9 Rabbit anti-Human Monoclonal (D2C9) Antibody
Human
IP, WB
Unconjugated
100 µl/$688
TLR9 Mouse anti-Human Monoclonal (aa1-815) (5G5) Antibody
Dog, Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$516
TLR9 Mouse anti-Human Monoclonal (aa1-815) (FITC) (5G5) Antibody
Dog, Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
FITC Conjugated
100 µg/$571
TLR9 Mouse anti-Human Monoclonal (N-Terminus) (TR9541) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-P, WB
Unconjugated
25 µg/$364; 100 µg/$511
TLR9 Mouse anti-Mouse Monoclonal (Concentrated) (5G5) Antibody
Mouse
Flo, IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$638
TLR9 Mouse anti-Human Monoclonal (aa1-815) (Biotin) (5G5) Antibody
Dog, Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Biotin Conjugated
50 µg/$429
TLR9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TLR9 Mouse anti-Mouse Monoclonal (Azide-free) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated, Azide-free
100 µg/$414
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