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TJP1 / ZO-1
tight junction protein 1
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
| Gene Name: | tight junction protein 1 |
| Family/Subfamily: | Occludin , Not assigned-Occludin |
| Synonyms: | TJP1, ZO-1, Zona occludens protein 1, Zona occludens 1, Zonula occludens protein 1, Tight junction protein 1, ZO1, Tight junction protein ZO-1, Zonula occludens 1 protein |
| Target Sequences: | NM_003257 NP_003248.3 Q07157 |
Publications (11)
1
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB. PloS one. 2015 10:e0121707. (ICC, IHC-P; Human)
[Full Text Article]
[PubMed:25826270]
[PMC:PMC4380339]
2
Tricellulin Expression and its Deletion Effects in the Endolymphatic Sac. Ai Matsubara, Takenori Miyashita, Ryuhei Inamoto, Hirofumi Sakaguchi, Toru Kamitani, Nozomu Mori, Hiroshi Hoshikawa. The journal of international advanced otology. 2018 August;14:312-316. [Full Text Article]
[PubMed:30100545]
[PMC:PMC6354451]
Related Antibodies: LS-C124822.
3
Reversal of cigarette smoke extract-induced sinonasal epithelial cell barrier dysfunction through Nrf2 Activation. Anuj Tharakan, Ashleigh A Halderman, Andrew P Lane, Shyam Biswal, Murugappan Ramanathan Jr. International forum of allergy & rhinology. 2016 November;6:1145-1150. [Full Text Article]
[PubMed:27580429]
[PMC:PMC5097009]
Related Antibodies: LS-C354905.
☰ Filters
Products
Proteins
(8)
Type
Over-Expression Lysate
(2)
Recombinant
(6)
Target
TJP1 / ZO-1
(8)
Publications
No
(8)
Tag
GST, N-terminus
(1)
His
(1)
His-S
(1)
His-T7
(1)
Myc-DDK (Flag)
(4)
Species
Dog
(1)
Human
(5)
Rat
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(3)
Wheat Germ Extract
(1)
E. coli
His-T7
24.7 kDa
10 µg/$285; 50 µg/$470; 200 µg/$937; 1 mg/$2,063; 5 mg/$3,277; 2 mg/$2,252
E. coli
His-S
56.4 kDa
10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
293T Cells
Myc-DDK (Flag)
195.3 kDa
20 µg/$215
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
195.3 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
186.8 kDa
20 µg/$1,107
E. coli
His
18.77 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
HEK 293 Cells
Myc-DDK (Flag)
195.3 kDa
100 µg/$710
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