SPHK / SPHK1

sphingosine kinase 1

SPHK / SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (57)

Type

Primary (57)

Target

SPHK / SPHK1 (57)

Reactivity

Human (53)

Mouse (30)

Rat (13)

Bovine (1)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Hamster (2)

Horse (3)

Monkey (13)

Primate (1)

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Application

IHC (21)

IHC-P (8)

WB (49)

Flo (2)

ELISA (18)

ICC (1)

IF (6)

IP (3)

Peptide-ELISA (2)

Host

rabbit (54)

mouse (2)

goat (1)

Product Group

IHCPlus (4)

Isotype

IgG (27)

IgG2a (2)

Clonality

monoclonal mc (2)

polyclonal pc (55)

Clone

OTI1A6 (2)

Format

APC (1)

APC Conjugated (3)

Biotin Conjugated (5)

Carrier-free (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (33)

Epitope

aa148-398 (8)

aa1-30 (7)

aa286-315 (7)

aa176-225 (4)

N-Terminus (3)

C-Terminus (1)

aa1-50 (1)

aa176-189 (1)

aa313-343 (1)

aa334-384 (1)

aa59-89 (1)

pSer225 (1)

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Publications

No (55)

Yes (2)

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IHC-plus™ SPHK / SPHK1 Antibody (N-Terminus) LS-A3106

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(5.0) Rating

(1) Publication(s)

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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SPHK / SPHK1 Antibody (aa286-315) LS-C100769

(4.0) Rating

(1) Publication(s)

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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SPHK / SPHK1 Antibody (phospho-Ser225) LS-C26925

Antibody:

SPHK / SPHK1 Rabbit anti-Mouse Polyclonal (pSer225) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$623

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SPHK / SPHK1 Antibody (aa176-189) LS-C87246

Antibody:

SPHK / SPHK1 Goat anti-Human Polyclonal (aa176-189) Antibody

Reactivity:

Mouse, Hamster, Human, Monkey

Applications:

IP, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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IHC-plus™ SPHK / SPHK1 Antibody LS-B6973

(4.0) Rating

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Hamster, Human, Monkey

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

1 Each/$485

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IHC-plus™ SPHK / SPHK1 Antibody (N-Terminus) LS-A3102

Fast Shipping

(4.0) Rating

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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SPHK / SPHK1 Antibody (FITC) LS-C146698

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, WB

Format:

FITC Conjugated

Price:

1 Each/$457

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SPHK / SPHK1 Antibody LS-C330808

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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SPHK / SPHK1 Antibody (clone OTI1A6) LS-C338427

Antibody:

SPHK / SPHK1 Mouse anti-Human Monoclonal (OTI1A6) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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SPHK / SPHK1 Antibody (clone OTI1A6, Carrier-free) LS-C788509

Antibody:

SPHK / SPHK1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A6) Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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SPHK / SPHK1 Antibody (aa313-343) LS-C161448

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa313-343) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SPHK / SPHK1 Antibody (aa59-89) LS-C100770

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa59-89) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SPHK / SPHK1 Antibody LS-C192442

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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SPHK / SPHK1 Antibody LS-C152974

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

50 µg/$631

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SPHK / SPHK1 Antibody LS-C499856

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IHC-plus™ SPHK / SPHK1 Antibody (N-Terminus) LS-A3104

Fast Shipping

(4.0) Rating

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

SPHK / SPHK1 Antibody (aa286-315) LS-C325332

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SPHK / SPHK1 Antibody (aa286-315, HRP) LS-C540615

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) (HRP) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$952

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SPHK / SPHK1 Antibody (aa286-315, Biotin) LS-C520472

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) (Biotin) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SPHK / SPHK1 Antibody (aa286-315, APC) LS-C270187

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) (APC) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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SPHK / SPHK1 Antibody (aa286-315, PE) LS-C270189

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal (aa286-315) (PE) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • PE

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SPHK / SPHK1 Antibody LS-C751895

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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SPHK / SPHK1 Antibody LS-C805942

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SPHK / SPHK1 Antibody LS-C770841

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SPHK / SPHK1 Antibody LS-C746745

Antibody:

SPHK / SPHK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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