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Prohibitin 2 / PHB2

prohibitin 2

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases By similarity. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Gene Name: prohibitin 2
Family/Subfamily: Transcription factor
Synonyms: PHB2, BCAP37, BAP, D-prohibitin, p22, Prohibitin-2, B-cell associated protein, Bap37, PNAS-141, Prohibitin 2, REA
Target Sequences: NM_007273 NP_001138303.1 Q99623

Publications (2)

1
Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein. Emerson V, Holtkotte D, Pfeiffer T, Wang IH, Schnlzer M, Kempf T, Bosch V. Journal of virology. 2010 84:1355-65. [PubMed:19906925] [PMC:PMC2812343] Related Antibodies: LS-B1889.
2
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes. Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM. Journal of immunology (Baltimore, Md. : 1950). 2013 190:723-36. [PubMed:23241883] [PMC:PMC3538926] Related Antibodies: LS-B1889.

☰ Filters
Products
Antibodies (42)
Primary (42)
Prohibitin 2 / PHB2 (42)
Human (41)
Mouse (18)
Rat (13)
Bat (6)
Bovine (9)
Chicken (3)
Chimpanzee (9)
Dog (9)
Drosophila (3)
Gibbon (9)
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Hamster (3)
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Monkey (6)
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Rabbit (10)
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IHC (19)
IHC-P (10)
WB (40)
ELISA (16)
ICC (5)
IF (2)
IP (5)
rabbit (41)
sheep (1)
Product Group
IHCPlus (4)
IgG (31)
polyclonal pc (42)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (23)
Tyr128 (7)
Tyr248 (7)
C-Terminus (5)
aa191-240 (4)
aa74-123 (4)
aa1-50 (2)
Internal (1)
aa1-299 (1)
aa111-128 (1)
aa225-275 (1)
aa250-C-term (1)
aa66-95 (1)
aa88-299 (1)
aa89-299 (1)
No (41)
Yes (1)
Prohibitin 2 / PHB2 Antibody - Anti-PHB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Prohibitin 2 / PHB2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$440
Prohibitin 2 / PHB2 Antibody - Anti-PHB2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa88-299) Antibody
Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$545
Prohibitin 2 / PHB2 Antibody - Human, Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
Prohibitin 2 / PHB2 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
Prohibitin 2 / PHB2 Antibody - Prohibitin 2 / PHB2 antibody. IHC(P): Human Lung Cancer Tissue.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa111-128) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Prohibitin 2 / PHB2 Antibody - PHB2 Antibody (Y248)immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr248) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Prohibitin 2 / PHB2 Antibody - Detection of Human REA by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-REA used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, IP
Unconjugated
10 µg/$295; 100 µl/$514
Prohibitin 2 / PHB2 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa74-123) Antibody
Human
WB
Unconjugated
100 µl/$424
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
Prohibitin 2 / PHB2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa1-299) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr128) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Prohibitin 2 / PHB2 Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PHB2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa66-95) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Prohibitin 2 / PHB2 Antibody
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (Tyr248) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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Prohibitin 2 / PHB2 Sheep anti-Human Polyclonal (aa89-299) Antibody
Rabbit, Mouse, Human
ELISA, WB
Unconjugated
100 µg/$930
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Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa225-275) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
Prohibitin 2 / PHB2 Rabbit anti-Human Polyclonal (aa250-C-term) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).