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PPP1R1B / DARPP-32

protein phosphatase 1, regulatory (inhibitor) subunit 1B

PPP1R1B / DARPP-32 is a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: protein phosphatase 1, regulatory (inhibitor) subunit 1B
Family/Subfamily: Protein Phosphatase Regulatory Subunit
Synonyms: PPP1R1B, DARPP-32, DARPP32
Target Sequences: NM_032192 NP_115568.2 Q9UD71

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Products
Antibodies (44)
Primary (44)
PPP1R1B / DARPP-32 (44)
Human (36)
Mouse (37)
Rat (35)
Bovine (6)
Chicken (4)
Crab-eating macaque (1)
Dog (5)
Guinea pig (1)
Hamster (1)
Horse (1)
Monkey (3)
Pig (3)
Primate (1)
Rabbit (1)
Sheep (1)
IHC (28)
IHC-Fr (1)
IHC-P (13)
WB (40)
Flo (1)
ELISA (13)
ICC (2)
IF (10)
IP (7)
Peptide-ELISA (7)
rabbit (40)
mouse (2)
goat (1)
rat (1)
Product Group
IHCPlus (1)
IgG (28)
IgG1 (2)
IgG2a (1)
monoclonal mc (4)
polyclonal pc (40)
2A4G9 (1)
2G6D9 (1)
APC Conjugated (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (39)
pThr75 (6)
pThr34 (5)
10-90 aa (3)
N-Terminus (2)
aa51-204 (2)
aa95-204 (2)
Glu160 (1)
Pro69 (1)
aa1-168 (1)
aa1-36 (1)
aa106-139 (1)
aa18-67 (1)
aa19-50 (1)
aa41-90 (1)
pSer137 (1)
No (44)
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PPP1R1B / DARPP-32 Rat anti-Human Monoclonal (aa51-204) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$896
PPP1R1B / DARPP-32 Antibody - Immunohistochemical analysis of DARPP32 (pT34) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr34) Antibody
Mouse, Bovine, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
PPP1R1B / DARPP-32 Antibody - Western blot of rat caudate lysate showing specific immunolabeling of the ~32k DARPP-32 phosphorylated at Thr34 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: l-Ptase). The blot is identical to the control except that it was incubated in l-Ptase (1200 units for 30 min) before being exposed to the Anti-Thr34 DARPP-32. The immunolabeling is completely eliminated by treatment with l-Ptase.
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PPP1R1B / DARPP-32 Rabbit anti-Rat Polyclonal (pThr34) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Human
IHC, WB
Unconjugated
100 µl/$469
PPP1R1B / DARPP-32 Antibody - Western blot of rat caudate lysate showing specific immunolabeling of the ~32k DARPP-32 phosphorylated at Thr75 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda phosphatase). The blot is identical
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PPP1R1B / DARPP-32 Rabbit anti-Rat Polyclonal (pThr75) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Human
IHC, WB
Unconjugated
100 µl/$469
PPP1R1B / DARPP-32 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Monoclonal (Glu160) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µl/$688
PPP1R1B / DARPP-32 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µl/$665
PPP1R1B / DARPP-32 Antibody - Immunohistochemical analysis of DARPP32 (pT75) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr75) Antibody
Mouse, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$315
PPP1R1B / DARPP-32 Antibody - 1:100 staining human colon carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr34) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PPP1R1B / DARPP-32 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using DARPP-32 (Phospho-Thr34) antibody.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr34) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
PPP1R1B / DARPP-32 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr75) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PPP1R1B / DARPP-32 Antibody - Western blot of Phospho-DARPP-32 (T34) antibody
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$332
PPP1R1B / DARPP-32 Antibody - DARPP32 was detected in paraffin-embedded sections of mouse pancreas tissues using rabbit anti- DARPP32 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (aa1-36) Antibody
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PPP1R1B / DARPP-32 Antibody - Western blot using PPP1R1B monoclonal antibody against human PPP1R1B (AA: 95-204) recombinant protein. (Expected MW is 38.3 kDa)
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PPP1R1B / DARPP-32 Mouse anti-Human Monoclonal (aa95-204) (2G6D9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
PPP1R1B / DARPP-32 Antibody - Immunochemical staining PPP1R1B in cynomolgus cerebellum with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
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PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Human, Crab-eating macaque
ICC, IF, IHC-P
Unconjugated
100 µl/$412
PPP1R1B / DARPP-32 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DARPP-32 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (aa41-90) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PPP1R1B / DARPP-32 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DARPP-32 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (aa18-67) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PPP1R1B / DARPP-32 Antibody
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PPP1R1B / DARPP-32 Antibody - Western blot of Phospho-DARPP-32 (T75) antibody
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PPP1R1B / DARPP-32 Antibody - Western blot of DARPP-32 antibody
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PPP1R1B / DARPP-32 Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using DARPP-32 (phospho-Thr75) antibody.
Select
PPP1R1B / DARPP-32 Rabbit anti-Human Polyclonal (pThr75) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PPP1R1B / DARPP-32 Antibody - Western blot using PPP1R1B monoclonal antibody against human PPP1R1B (AA: 95-204) recombinant protein. (Expected MW is 38.3 kDa)
Select
PPP1R1B / DARPP-32 Mouse anti-Human Monoclonal (aa95-204) (2A4G9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).