PODXL / Podocalyxin

podocalyxin-like

Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

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Products

Antibodies (88)

ELISA Kits (28)

Proteins (11)

Type

Competitive EIA (3)

Custom (4)

Development Kit (1)

Over-Expression Lysate (2)

Primary (88)

Recombinant (9)

Sandwich (17)

Sandwich CLIA (3)

Target

PODXL / Podocalyxin (127)

Reactivity

Human (80)

Mouse (26)

Rat (24)

Chicken (2)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Hamster (1)

Horse (1)

Monkey (5)

Porcine (1)

Rabbit (10)

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Application

IHC (35)

IHC-P (23)

WB (69)

Flo (20)

ELISA (21)

ICC (1)

IF (11)

IP (4)

Peptide-ELISA (1)

Host

rabbit (56)

mouse (31)

goat (1)

Product Group

DevKit DuoPlus (1)

IHCPlus (1)

PathPlus Cancer (1)

PathPlus Cancer Pathology (1)

Isotype

IgG (24)

IgG1 (17)

IgG1,k (1)

IgG2a (5)

IgG2b (1)

IgM (7)

Clonality

monoclonal mc (31)

polyclonal pc (57)

Clone

2A4 (3)

3D3 (3)

4D2G7 (1)

4F10 (3)

4H11 (1)

53D11 (3)

5D4 (2)

5F5 (2)

OTI2C6 (2)

OTI8D6 (2)

OTI9C2 (2)

PODXL/2185 (2)

SPM487 (1)

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Format

12 x 8-Well Microstrips (3)

96-Well Microplate (5)

96-Well Strip Plate (19)

Antibody Pair and Standard (1)

APC (3)

APC Conjugated (4)

Azide-free (4)

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Ready-to-Use (3)

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Epitope

Extracellular Domain (10)

aa153-386 (8)

aa171-404 (8)

aa220-463 (8)

aa410-439 (8)

aa32-461 (6)

Internal (4)

aa131-180 (4)

aa301-350 (4)

C-Terminus (1)

aa100-200 (1)

aa543-557 (1)

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Publications

No (127)

Sample Type

Cell Culture Supernatants (5)

Cell Lysates (4)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (15)

Serum (17)

Tissue Homogenates (8)

Urine (3)

Tag

6His, N-terminus (3)

DDK (Flag)-His, C-terminus (2)

His, N-Terminal (1)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Rat (2)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (4)

Yeast (2)

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PathPlus™ PODXL / Podocalyxin Antibody (clone 53D11) LS-B9427

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (53D11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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PODXL / Podocalyxin Antibody (Extracellular Domain) LS-C75196

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) Antibody

Reactivity:

Human

Applications:

Flo, ICC, WB

Format:

Unconjugated

Price:

100 µg/$962

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PODXL / Podocalyxin Antibody (clone 53D11, FITC) LS-C179809

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (FITC) (53D11) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

100 µl/$430

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Human PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F4763

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates, Urine

Price:

1 Plate/$764

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Mouse PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F6775

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$782

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Rat PODXL / Podocalyxin Protein (Recombinant 6His, N-terminus) (aa25-386) - LS-G23485

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

39.82 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human PODXL / Podocalyxin Protein (Recombinant 6His, N-terminus) (aa32-458) - LS-G23358

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

46.2 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human PODXL / Podocalyxin Protein (Recombinant 6His, N-terminus) (aa32-458) - LS-G22600

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

48.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Rat PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F53935

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Serum, Urine

Price:

1 Plate/$1,041

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PODXL / Podocalyxin Antibody (clone 53D11, PE) LS-C179810

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (PE) (53D11) Antibody

Reactivity:

Human

Applications:

Flo

Format:

PE Conjugated

Price:

1 ml/$451

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PODXL / Podocalyxin Antibody (Internal, Biotin) LS-C141161

Antibody:

PODXL / Podocalyxin Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

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PODXL / Podocalyxin Antibody (Extracellular Domain, clone 3D3) LS-C358018

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (3D3) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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PODXL / Podocalyxin Antibody (Extracellular Domain, clone 3D3, Ready-to-Use) LS-C389664

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (3D3) Antibody

Reactivity:

Rabbit, Rat, Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

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PODXL / Podocalyxin Antibody (Extracellular Domain, clone 3D3, Azide-free, BSA-free) LS-C389666

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (3D3) Antibody

Reactivity:

Rabbit, Rat, Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

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PODXL / Podocalyxin Antibody (aa301-350) LS-B3558

Antibody:

PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa301-350) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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Rat PODXL / Podocalyxin Protein (Recombinant His, N-Terminal) (aa153-386) - LS-G12773

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.4 kDa

Price:

10 µg/$282; 50 µg/$447; 200 µg/$892; 1 mg/$2,005; 5 mg/$3,123; 2 mg/$2,192

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PODXL / Podocalyxin Antibody (clone SPM487) LS-C50321

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (SPM487) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$455

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PODXL / Podocalyxin Antibody (aa543-557) LS-C55300

Antibody:

PODXL / Podocalyxin Goat anti-Human Polyclonal (aa543-557) Antibody

Reactivity:

Rabbit, Mouse, Hamster, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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Mouse PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F57343

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

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PODXL / Podocalyxin Antibody (aa410-439, Biotin) LS-C520423

Antibody:

PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa410-439) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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Rat PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F9804

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$715

Select

Rat PODXL / Podocalyxin (Sandwich ELISA) ELISA Kit - LS-F20799

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse PODXL / Podocalyxin (Competitive EIA) ELISA Kit - LS-F28533

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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PODXL / Podocalyxin Antibody (clone 4H11) LS-C179811

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (4H11) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$423

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PODXL / Podocalyxin Antibody (clone 4D2G7) LS-C681784

Antibody:

PODXL / Podocalyxin Mouse anti-Human Monoclonal (4D2G7) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$316; 100 µl/$386

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