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NGFR / CD271 / TNR16
nerve growth factor receptor
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
| Gene Name: | nerve growth factor receptor |
| Family/Subfamily: | TNF Receptor , not assigned-TNF Receptor |
| Synonyms: | NGFR, CD271, CD271 antigen, gp80-LNGFR, Nerve growth factor receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, NGF receptor, TNFRSF16, p75-NTR |
| Target Sequences: | NM_002507 NP_002498.1 P08138 |
Publications (3)
1
Platelet-derived growth factor receptor-a and -ß promote cancer stem cell phenotypes in sarcomas. Chang KK, Yoon C, Yi BC, Tap WD, Simon MC, Yoon SS. Oncogenesis. 2018 June;7:47. (Human)
[Full Text Article]
[PubMed:29915281]
[PMC:PMC6006341]
Related Antibodies: LS-C109106.
2
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Nicolas Severe, Nezihi Murat Karabacak, Karin Gustafsson, Ninib Baryawno, Gabriel Courties, Youmna Kfoury, Konstantinos D Kokkaliaris, Catherine Rhee, Dongjun Lee, Elizabeth W Scadden, Juan Esteban Garcia-Robledo, Thomas Brouse, Matthias Nahrendorf, Mehmet Toner, David T Scadden. Cell stem cell. 2019 October;25:570-583.e7. [Full Text Article]
[PubMed:31279774]
[PMC:PMC6778015]
Related Antibodies: LS-C179536.
3
Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression. Annalisa Saltari, Andreas Dzung, Marika Quadri, Natascia Tiso, Nicola Facchinello, Alberto Hernández-Barranco, Susana Garcia-Silva, Laura Nogués, Corinne Isabelle Stoffel, Phil F Cheng, Patrick Turko, Ossia M Eichhoff, Francesca Truzzi , Alessandra Marconi, Carlo Pincelli, Héctor Peinado, Reinhard Dummer, Mitchell P Levesque. The Breast : official journal of the European Society of Mastology. 2021 Dec;81:6044-6057. [Full Text Article]
[PubMed:34645608]
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NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (2F1C2) Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
100 µl/$435
NGFR / CD271 / TNR16 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
NGFR / CD271 / TNR16 Rat anti-Mouse Monoclonal (25-8) Antibody
Mouse
Flo
Unconjugated
100 µl/$425
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NGFR / CD271 / TNR16 Rabbit anti-Rat Polyclonal (aa274-425) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$896
Cancer Pathology
Cancer
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (NGFR5) Antibody
Rabbit, Feline, Ferret, Non-Human Primates, Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal Antibody
Human
ICC, IHC, WB
Unconjugated
50 µg/$957
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (ME20.4) Antibody
Rabbit, Dog, Pig, Cat, Raccoon, Human, Monkey
Flo, IHC, WB
Unconjugated
150 µg/$393
NGFR / CD271 / TNR16 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
200 µl/$939
NGFR / CD271 / TNR16 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC
Unconjugated
100 µl/$688
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (Concentrated) (MRQ-21) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
1 ml/$1,659
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (CDLA271) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (NGFR5 + NTR/912) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
NGFR / CD271 / TNR16 Goat anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
50 µg/$1,022
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
32-60 kDa (SDS-PAGE)
50 µg/$342; 10 µg/$262; 1 mg/$2,449
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (Biotin) (NGFR5) Antibody
Rabbit, Feline, Ferret, Non-Human Primates, Human
Flo, ICC, IHC-P, IP, WB
Biotin Conjugated
0.1 mg/$337
Cancer Pathology
Cancer
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal Antibody
Human, Monkey
IHC-P, IP, Neut, WB
Unconjugated
50 µg/$485
NGFR / CD271 / TNR16 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Cancer Pathology
Cancer
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$460
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$325
NGFR / CD271 / TNR16 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
NGFR / CD271 / TNR16 Goat anti-Human Polyclonal (aa342-353) Antibody
Dog, Bovine, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
NGFR / CD271 / TNR16 Goat anti-Human Polyclonal (aa202-215) Antibody
Rat, Hamster, Horse, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
NGFR / CD271 / TNR16 Mouse anti-Human Monoclonal (2F1C2) Antibody
Human
Flo, ICC, IF, WB
Unconjugated
100 µl/$541
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