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NEFM / NF-M

neurofilament, medium polypeptide

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: neurofilament, medium polypeptide
Synonyms: NEFM, 160 kDa neurofilament protein, NEF3, NF-M, NFM, Neurofilament 3
Target Sequences: NM_005382 NP_005373.2 P07197

Publications (3)

1
Enhancement of the growth and differentiation of nasal olfactory mucosa cells by the conjugation of growth factors to functional nanoparticles. Skaat H, Ziv-Polat O, Shahar A, Margel S. Bioconjugate chemistry. 2011 22:2600-10. (ICC; Rat) [PubMed:22029397]
2
Novel magnetic fibrin hydrogel scaffolds containing thrombin and growth factors conjugated iron oxide nanoparticles for tissue engineering. Ziv-Polat O, Skaat H, Shahar A, Margel S. International journal of nanomedicine. 2012 7:1259-74. (ICC; Rat) [PubMed:22419873] [PMC:PMC3298389]
3
Neurofilament protein levels: quantitative analysis in essential tremor cerebellar cortex. Louis ED, Ma K, Babij R, Corts E, Liem RK, Vonsattel JP, Faust PL. Neuroscience letters. 2012 518:49-54. (IHC, WB; Human) [PubMed:22561033] [PMC:PMC3364538]

☰ Filters
Products
Antibodies (75)
Primary (75)
NEFM / NF-M (75)
Human (68)
Mouse (30)
Rat (42)
Avian (1)
Bat (3)
Bird (1)
Bovine (7)
Cat (1)
Chicken (10)
Chimpanzee (6)
Dog (1)
Guinea pig (5)
Hamster (5)
Horse (1)
Mammal (4)
Monkey (8)
Orangutan (3)
Pig (5)
Rabbit (13)
Sheep (3)
Xenopus (4)
IHC (38)
IHC-Fr (8)
IHC-P (14)
WB (67)
Flo (9)
ELISA (22)
ICC (10)
IF (19)
IP (12)
Peptide-ELISA (3)
rabbit (26)
mouse (42)
goat (1)
chicken (6)
Product Group
PathPlus Neuro (3)
IgG (9)
IgG1 (26)
IgG1,k (7)
IgG2a (2)
IgG2a,k (6)
IgY (3)
monoclonal mc (42)
polyclonal pc (33)
1B6B12 (1)
3H11 (1)
403 (1)
NF-09 (2)
OTI1A4 (2)
OTI2C4 (2)
OTI2G3 (2)
OTI5B7 (2)
OTI5H4 (2)
RMO 14.9 (1)
RNF403 (1)
RNF406 (1)
APC (1)
APC Conjugated (4)
Biotin Conjugated (6)
Carrier-free (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Preservative Free (1)
Unconjugated (47)
C-Terminus (12)
aa105-287 (8)
aa413-773 (6)
aa429-478 (4)
Internal (1)
Lys591 (1)
aa250-263 (1)
aa542-591 (1)
No (75)
NEFM / NF-M Antibody - Anti-NEFM / NF-M antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Neuroscience
NEFM / NF-M Mouse anti-Human Monoclonal (RNF406) Antibody
Xenopus, Hamster, Rabbit, Guinea pig, Human, Monkey
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
NEFM / NF-M Antibody - Anti-NEFM / NF-M antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Neuroscience
NEFM / NF-M Mouse anti-Human Monoclonal (RNF403) Antibody
Xenopus, Hamster, Human, Monkey
IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$440
NEFM / NF-M Antibody - Anti-NEFM / NF-M antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Neuroscience
NEFM / NF-M Goat anti-Human Polyclonal (aa250-263) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
NEFM / NF-M Antibody - Immunohistochemistry analysis of the neurofilament medium chain showing staining in the filaments of paraffin-embedded human brain tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0) and microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Neurofilament medium chain monoclonal antibody diluted in 3% BSA-PBS at a dilution of 1:20 overnight at 4°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.
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NEFM / NF-M Mouse anti-Rat Monoclonal (RMO 14.9) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$504
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NEFM / NF-M Mouse anti-Rat Monoclonal Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$842
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (HRP) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
HRP Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (Biotin) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
Biotin Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (FITC) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
FITC Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (APC) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
APC Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (PE) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ELISA, IF, IHC, WB
PE Conjugated
100 µl/$1,063
NEFM / NF-M Antibody - IHC of paraffin-embedded Human skin tissue using anti-NEFM mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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NEFM / NF-M Mouse anti-Human Monoclonal (aa413-773) (OTI5B7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
NEFM / NF-M Antibody - Immunohistochemical staining of paraffin-embedded Human skin tissue using anti-NEFM mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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NEFM / NF-M Mouse anti-Human Monoclonal (aa413-773) (Carrier-free) (OTI5B7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NEFM / NF-M Antibody - Section of rat cerebral cortex stained with NEFM / NF-M antibody (red), which reveals the perikarya of pyramidal neurons and dendrites and axons surrounding them. The green channel shows staining with a monoclonal antibody to the beta-adrenergic receptor kinase 1.
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NEFM / NF-M Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$376
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NEFM / NF-M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
Select
NEFM / NF-M Mouse anti-Rat Monoclonal Antibody
Rat, Human
ELISA, Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$842
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (HRP) Antibody
Rat, Human
ELISA, Flo, IHC, IP, WB
HRP Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (Biotin) Antibody
Rat, Human
ELISA, Flo, IHC, IP, WB
Biotin Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (FITC) Antibody
Rat, Human
ELISA, Flo, IHC, IP, WB
FITC Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (APC) Antibody
Rat, Human
ELISA, Flo, IHC, IP, WB
APC Conjugated
100 µl/$1,063
Select
NEFM / NF-M Mouse anti-Rat Monoclonal (PE) Antibody
Rat, Human
ELISA, Flo, IHC, IP, WB
PE Conjugated
100 µl/$1,063
NEFM / NF-M Antibody - IHC of paraffin-embedded Human skin tissue using anti-NEFM mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
NEFM / NF-M Mouse anti-Human Monoclonal (aa413-773) (OTI2G3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
NEFM / NF-M Antibody - Immunohistochemical staining of paraffin-embedded Human skin tissue using anti-NEFM mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Select
NEFM / NF-M Mouse anti-Human Monoclonal (aa413-773) (Carrier-free) (OTI2G3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
NEFM / NF-M Mouse anti-Human Monoclonal Antibody
Xenopus, Hamster, Human, Monkey
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$658
Select
NEFM / NF-M Mouse anti-Rat Monoclonal Antibody
Rat, Human
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
200 µg/$842
NEFM / NF-M Antibody - Culture of adult neural cells grown as described (2). Mature neurons can be identified by their morphology and because they stain strongly with antibodies to NF-L, NF-M and NF-H. The surrounding stellate red cells are stained with rabbit polyclonal Rat facial nucleus. These are apparently mitotic neuronal progenitor cells and express many other neuronal markers.
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NEFM / NF-M Mouse anti-Human Monoclonal (3H11) Antibody
Bird, Mammal
ICC, IF, WB
Unconjugated
100 µl/$376
Viewing 1-25 of 75 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).