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ME1 / Malate Dehydrogenase

malic enzyme 1, NADP(+)-dependent, cytosolic

ME1 / Malate Dehydrogenase encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Gene Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Synonyms: ME1, HUMNDME, Malate dehydrogenase, Malic enzyme 1, Malate oxidoreductase, Malic enzyme 1, soluble, MES, NADP-ME, Pyruvic-malic carboxylase, NADP-dependent malic enzyme, Malic enzyme, cytoplasmic
Target Sequences: NM_002395 NP_002386.1 P48163

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Products
Antibodies (36)
Primary (36)
ME1 / Malate Dehydrogenase (36)
Human (30)
Mouse (7)
Rat (7)
Chimpanzee (6)
Dog (3)
Gibbon (3)
Monkey (3)
Orangutan (3)
Pig (9)
Rabbit (3)
IHC (7)
IHC-P (3)
WB (32)
ELISA (16)
ICC (1)
IF (2)
IP (7)
Peptide-ELISA (3)
rabbit (29)
mouse (1)
sheep (6)
Ig (1)
IgG (28)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (35)
3H5 (1)
APC Conjugated (1)
Biotin Conjugated (6)
FITC Conjugated (4)
HRP Conjugated (6)
Liquid (3)
Lyophilized (3)
PE Conjugated (1)
Unconjugated (18)
aa246-295 (4)
aa36-85 (4)
440-520 aa, C-terminal (1)
N-Terminus (1)
Tyr500 (1)
aa161-519 (1)
aa451-500 (1)
aa468-517 (1)
No (36)
ME1 / Malate Dehydrogenase Antibody - Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 ug/mL.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
ME1 / Malate Dehydrogenase Antibody - IHC of paraffin-embedded Cal27 xenograft using ME1 antibody at 1:500 dilution.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (aa161-519) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ME1 / Malate Dehydrogenase Antibody - Immunoperoxidase of monoclonal antibody to ME1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 0.5 ug/ml]
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ME1 / Malate Dehydrogenase Mouse anti-Human Monoclonal (3H5) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
ME1 / Malate Dehydrogenase Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer at dilution of 1:100
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
ME1 / Malate Dehydrogenase Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Lyophilized) (HRP) Antibody
Pig
ELISA, IHC, IP, WB
HRP Conjugated, Lyophilized
100 µg/$552
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Liquid) (HRP) Antibody
Pig
ELISA, IHC, IP, WB
HRP Conjugated, Liquid
25 µl/$304
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (440-520 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ME1 / Malate Dehydrogenase Antibody - Anti-ME1 Antibody (N-Term) at 1:2000 dilution + Caco2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
ME1 / Malate Dehydrogenase Antibody - Western blot analysis of extracts from HeLa cells, using ME1 antibody.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ME1 / Malate Dehydrogenase Antibody - Western Blot of Sheep anti-Malate Dehydrogenase antibody. Lane 1: Malate Dehydrogenase. Lane 2: None. Load: 50 ng per lane. Primary antibody: Malate Dehydrogenase antibody at 1:1,000 for overnight at 4°C. Secondary antibody: Peroxidase sheep secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 36 kDa, 36 kDa for Malate Dehydrogenase. Other band(s): None.
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Lyophilized) Antibody
Pig
ELISA, IP, WB
Unconjugated, Lyophilized
100 µg/$567
ME1 / Malate Dehydrogenase Antibody - Western Blot of Sheep anti-Malate Dehydrogenase antibody. Lane 1: Malate Dehydrogenase. Lane 2: None. Load: 50 ng per lane. Primary antibody: Malate Dehydrogenase antibody at 1:1,000 for overnight at 4°C. Secondary antibody: Peroxidase sheep secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 36 kDa, 36 kDa for Malate Dehydrogenase. Other band(s): None.
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Liquid) Antibody
Pig
ELISA, IP, WB
Unconjugated, Liquid
25 µl/$304
ME1 / Malate Dehydrogenase Antibody - Western blot analysis of lysates from HeLa cells, using ME1 Antibody. The lane on the right is blocked with the synthesized peptide.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (aa468-517) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ME1 / Malate Dehydrogenase Antibody - Western blot analysis of the lysates from HeLa cells using ME1 antibody.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (aa451-500) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Liquid) (Biotin) Antibody
Pig
ELISA, IP, WB
Biotin Conjugated, Liquid
25 µl/$304
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ME1 / Malate Dehydrogenase Sheep anti-Pig Polyclonal (Lyophilized) (Biotin) Antibody
Pig
ELISA, IP, WB
Biotin Conjugated, Lyophilized
100 µg/$547
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
ME1 / Malate Dehydrogenase Antibody - ME1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
ME1 / Malate Dehydrogenase Antibody
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
ME1 / Malate Dehydrogenase Antibody - Western blot of Malic enzyme 1 (Y500) pAb in extracts from HeLa cells.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (Tyr500) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ME1 / Malate Dehydrogenase Antibody - Western blot of Human Lymph Node Tumor. ME1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ME1 / Malate Dehydrogenase Rabbit anti-Human Polyclonal (aa246-295) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 36 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).