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Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes.
Gene Name: | leukemia inhibitory factor |
Synonyms: | LIF, DIA, Emfilermin, HILDA, Melanoma-derived LPL inhibitor, MLPLI, Leukemia inhibitory factor, CDF, D factor, Human interleukin in DA cells |
Target Sequences: | NM_002309 NP_002300.1 P15018 |
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