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Leptin
Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
| Gene Name: | Leptin |
| Synonyms: | LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB |
| Target Sequences: | NM_000230 NP_000221.1 P41159 |
Publications (6)
1
Leptin as a potential target for estrogen receptor-positive breast cancer. Yom CK, Lee KM, Han W, Kim SW, Kim HS, Moon BI, Jeong KY, Im SA, Noh DY. Journal of breast cancer. 2013 16:138-45. (WB; Human)
[Full Text Article]
[PubMed:23843844]
[PMC:PMC3706857]
Related Antibodies: LS-C25172.
2
Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Jones HN, Olbrych SK, Smith KL, Cnota JF, Habli M, Ramos-Gonzales O, Owens KJ, Hinton AC, Polzin WJ, Muglia LJ, Hinton RB. Placenta. 2015 36:1078-86. (WB; Mouse)
[Full Text Article]
[PubMed:26278057]
Related Antibodies: LS-B1459.
3
Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse. Bello AR, Puertas-Avendaño RA, González-Gómez MJ, González-Gómez M, Laborda J, Damas C, Ruiz-Hidalgo M, Diaz C. Journal of neuroendocrinology. 2017 August;29: [Full Text Article]
[PubMed:28718206]
[PMC:PMC6084355]
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Publications
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(164)
Yes
(2)
Leptin Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$480
Leptin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500 µg/$460
Leptin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Leptin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Leptin Mouse anti-Human Monoclonal (3G1-1C9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Leptin Goat anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
Leptin Goat anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
Leptin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
Leptin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
Leptin Rabbit anti-Cow Polyclonal (aa29-160) Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
Leptin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
250 µg/$503
Leptin Rabbit anti-Human Polyclonal (aa8-37) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Leptin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Pig, Human, Monkey
ELISA, IP, RIA, WB
Unconjugated
100 µl/$574
Leptin Mouse anti-Human Monoclonal (AT7E10) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
Leptin Rabbit anti-Human Polyclonal (aa57-92) Antibody
Human
IF, IHC
Unconjugated
50 µl/$860
Leptin Mouse anti-Human Monoclonal (YD-HLEP4B6) Antibody
Human
ELISA, IP, WB
Unconjugated
500 µg/$763; 1 mg/$957
Leptin Rabbit anti-Human Polyclonal (aa134-166) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
Leptin Rabbit anti-Mouse Polyclonal (aa74-109) Antibody
Mouse
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
Leptin Rabbit anti-Human Polyclonal (aa36-85) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Leptin Mouse anti-Human Monoclonal (4F12) Antibody
Human
ELISA
Unconjugated
0.2 mg/$611; 0.5 mg/$845
Leptin Rat anti-Mouse Monoclonal (aa22-167) (C4) Antibody
Mouse
WB
Unconjugated
100 µl/$307; 200 µl/$348; 500 µl/$486; 1 ml/$555; 2 ml/$742; 5 ml/$1,205
Leptin Rabbit anti-Human Polyclonal (aa8-37) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Leptin Rabbit anti-Human Polyclonal (aa8-37) (PE) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
PE Conjugated
200 µl/$952
Leptin Rabbit anti-Human Polyclonal (aa8-37) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Leptin Rabbit anti-Human Polyclonal (aa8-37) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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of 166
product results
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