Human IgG Fc

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. In IgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and a-2,6 linked sialic acid residues.

Human IgG Fc Target Details

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Products

Antibodies (239)

Type

Secondary (239)

Target

Human IgG Fc (239)

Reactivity

Human (230)

Sheep (8)

Application

IHC (136)

IHC-Fr (22)

IHC-P (3)

WB (128)

Flo (78)

DB (17)

DD (2)

ELISA (177)

EM (4)

FLISA (21)

ICC (60)

ID (33)

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IF (85)

IP (27)

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rabbit (37)

mouse (58)

goat (132)

chicken (6)

human (1)

pig (4)

sheep (1)

Product Group

Anti-Human Immunoglobulin (IgG/IgM) Antibodies (19)

Coronavirus Antibodies Proteins cDNAs (19)

Isotype

F(ab')2 (15)

IgG (105)

IgG F(ab')2 (7)

IgG Fc (1)

IgG1 (32)

IgG1,k (2)

IgG2a (1)

IgG2b (10)

IgG2b,k (1)

IgY (1)

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monoclonal mc (59)

polyclonal pc (180)

Clone

27B11E9 (1)

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3D8.H7.D4 (1)

4A10 (3)

4D2D9G8 (2)

50B4A9 (1)

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EM-07 (5)

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JDC-10 (5)

Format

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DY755 Conjugated (1)

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SPRD Conjugated (1)

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TRITC Conjugated (15)

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Publications

No (239)

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Rabbit Anti-Human IgG Fc Secondary Antibody LS-C60585

Antibody:

Human IgG Fc Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, IHC, WB

Format:

Unconjugated

Price:

5 mg/$400

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone JDC-10, AP) LS-C351361

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (AP) (JDC-10) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

AP Conjugated

Price:

1 ml/$360

Select

Goat Anti-Human IgG Fc Secondary Antibody LS-C60501

Antibody:

Human IgG Fc Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

1 mg/$301

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Goat Anti-Human IgG Fc Secondary Antibody (RPE) LS-C61388

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (RPE) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

RPE Conjugated

Price:

500 µg/$499

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Mouse Anti-Human IgG Fc Secondary Antibody (HRP) LS-C69862

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr

Format:

HRP Conjugated

Price:

100 µl/$786

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Goat Anti-Human IgG Fc Secondary Antibody (Biotin) LS-C61384

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

1 mg/$417

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone H2, PE) LS-C351397

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (PE) (H2) Antibody

Reactivity:

Human

Applications:

FLISA, Flo

Format:

PE Conjugated

Price:

0.1 mg/$395

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone JDC-10, PE) LS-C351363

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (PE) (JDC-10) Antibody

Reactivity:

Human

Applications:

FLISA, Flo

Format:

PE Conjugated

Price:

0.1 mg/$395

Select

Mouse Anti-Human IgG Fc Secondary Antibody LS-C69574

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

1 mg/$702

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone H2, AP) LS-C351372

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (AP) (H2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

AP Conjugated

Price:

1 ml/$360

Select

Rabbit Anti-Human IgG Fc Secondary Antibody (HRP) LS-C60603

Antibody:

Human IgG Fc Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

DB, ELISA, EM, IHC, WB

Format:

HRP Conjugated

Price:

2 mg/$376

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone 4A10) LS-C108752

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (4A10) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µl/$435

Select

Goat Anti-Human IgG Fc Secondary Antibody (HRP) LS-C59915

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

2 mg/$352

Select

Goat Anti-Human IgG Fc Secondary Antibody (Biotin) LS-C60516

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

1 mg/$342

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone 2E4) LS-C171461

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (2E4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 ml/$393

Select

Goat Anti-Human IgG Fc Secondary Antibody (HRP) LS-C56823

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC-Fr, WB

Format:

HRP Conjugated

Price:

1 mg/$356

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone H2, Azide-free, Low Endotoxin) LS-C351425

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (Azide-free, Low Endotoxin) (H2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IHC, IHC-Fr, WB

Format:

Unconjugated, Azide-free, Low Endotoxin

Price:

0.5 mg/$400

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone 5E661) LS-C69656

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (5E661) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

500 µg/$533

Select

Mouse Anti-Human IgG Fc Secondary Antibody LS-C69657

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

500 µg/$485

Select

Rabbit Anti-Human IgG Fc Secondary Antibody (HRP) LS-C212378

Antibody:

Human IgG Fc Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

500 µg/$295

Select

Rabbit Anti-Human IgG Fc Secondary Antibody (Biotin) LS-C60619

Antibody:

Human IgG Fc Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

DB, ELISA, EM, IHC, WB

Format:

Biotin Conjugated

Price:

2 mg/$360

Select

Goat Anti-Human IgG Fc Secondary Antibody (AP) LS-C60513

Antibody:

Human IgG Fc Goat anti-Human Polyclonal (AP) Antibody

Reactivity:

Human

Applications:

DB, ELISA, EM, IHC, WB

Format:

AP Conjugated

Price:

500 µg/$333

Select

Rabbit Anti-Human IgG Fc Secondary Antibody LS-C69947

Antibody:

Human IgG Fc Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

5 mg/$602

Select

Goat Anti-Human IgG Fc Secondary Antibody LS-C69819

Antibody:

Human IgG Fc Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

5 mg/$584

Select

Mouse Anti-Human IgG Fc Secondary Antibody (clone 50B4A9, HRP) LS-C742124

Antibody:

Human IgG Fc Mouse anti-Human Monoclonal (HRP) (50B4A9) Antibody

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$307

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