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GJA1 / CX43 / Connexin 43
gap junction protein, alpha 1, 43kDa
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.
| Gene Name: | gap junction protein, alpha 1, 43kDa |
| Family/Subfamily: | Ion Channel , Connexin |
| Synonyms: | GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3 |
| Target Sequences: | NM_000165 NP_000156.1 P17302 |
Publications (4)
1
Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex. Liu X, Sun L, Torii M, Rakic P. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:8280-5.
[PubMed:22566616]
[PMC:PMC3361458]
Related Antibodies: LS-C97725.
2
Inhibition of Connexin 43 and Phosphorylated NR2B in Spinal Astrocytes Attenuates Bone Cancer Pain in Mice. Yang H, Yan H, Li X, Liu J, Cao S, Huang B, Huang D, Wu L. Frontiers in cellular neuroscience. 2018 May;12:129. (Rat)
[Full Text Article]
[PubMed:29867362]
[PMC:PMC5951934]
Related Antibodies: LS-B9771.
3
Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing. Meike Baur, Birte Weber, Ina Lackner, Florian Gebhard, Roman Pfeifer, Paolo Cinelli, Sascha Halvachizadeh, Michel Teuben, Miriam Lipiski, Nikola Cesarovic, Hans-Christoph Pape, Miriam Kalbitz. PloS one. 2020 June;15:e0235220. [Full Text Article]
[PubMed:32584885]
[PMC:PMC7316303]
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Products
Antibodies
(123)
Type
Primary
(123)
Target
GJA1 / CX43 / Connexin 43
(123)
Reactivity
Human
(107)
Mouse
(90)
Rat
(78)
Bat
(8)
Bovine
(7)
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(4)
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(6)
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(1)
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(24)
Gibbon
(6)
Guinea pig
(9)
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(6)
Horse
(4)
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(13)
Pig
(16)
Rabbit
(10)
Sheep
(1)
Application
IHC
(56)
IHC-Fr
(2)
IHC-P
(30)
WB
(110)
Flo
(1)
ELISA
(44)
ICC
(13)
IF
(27)
IP
(4)
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(8)
Host
rabbit
(100)
mouse
(20)
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(3)
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IHCPlus
(7)
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(51)
IgG1
(12)
IgG1,k
(7)
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(1)
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monoclonal mc
(20)
polyclonal pc
(103)
Clone
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(1)
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(2)
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(3)
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(8)
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(10)
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(3)
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(3)
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(10)
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(10)
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(1)
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(8)
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(1)
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(1)
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(67)
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aa180-382
(24)
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(17)
aa107-138
(8)
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(5)
aa91-140
(4)
300-380 aa
(2)
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(2)
aa233-382
(2)
aa366-382
(2)
pSer261
(2)
200-280 aa
(1)
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(1)
310-390 aa, C-terminal
(1)
Ab-261
(1)
Arg361
(1)
Lys257
(1)
aa226-275
(1)
aa252-270
(1)
aa333-346
(1)
aa333-382
(1)
aa340-390
(1)
aa351-367
(1)
p367
(1)
pSer265
(1)
pTyr265
(1)
Publications
No
(120)
Yes
(3)
GJA1 / CX43 / Connexin 43 Goat anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
GJA1 / CX43 / Connexin 43 Goat anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µg/$460
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Fast Shipping
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa107-138) (PE) Antibody
Human
ELISA, IHC, IHC-P, WB
PE Conjugated
200 µl/$952
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa107-138) (AP) Antibody
Human
ELISA, IHC, IHC-P, WB
AP Conjugated
200 µl/$952
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa107-138) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa340-390) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$440
GJA1 / CX43 / Connexin 43 Mouse anti-Mouse Monoclonal (aa252-270) Antibody
Mouse, Dog, Rat, Pig, Human
ELISA, ICC, IHC, IHC-Fr, WB
Unconjugated
100 µg/$842
GJA1 / CX43 / Connexin 43 Mouse anti-Mouse Monoclonal (PE) Antibody
Mouse, Rat, Pig, Human
ELISA, ICC, IHC, WB
PE Conjugated
100 µl/$1,085
GJA1 / CX43 / Connexin 43 Mouse anti-Mouse Monoclonal (APC) Antibody
Mouse, Dog, Rat, Pig, Human
ELISA, ICC, IHC, WB
APC Conjugated
100 µl/$1,085
GJA1 / CX43 / Connexin 43 Goat anti-Human Polyclonal (aa333-346) Antibody
Rabbit, Dog, Guinea pig, Rat, Pig, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (Lys257) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Fast Shipping
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Human
IHC, IHC-P
Unconjugated
50 µg/$460
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa333-382) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (pTyr265) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (aa351-367) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GJA1 / CX43 / Connexin 43 Mouse anti-Rat Monoclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
100 µg/$890
GJA1 / CX43 / Connexin 43 Mouse anti-Rat Monoclonal (PE) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, WB
PE Conjugated
100 µl/$1,129
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (pSer367) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal (300-380 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
GJA1 / CX43 / Connexin 43 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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product results
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