FTO

fat mass and obesity associated

Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.

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Products

Antibodies (32)

Type

Primary (32)

Target

FTO (32)

Reactivity

Human (29)

Mouse (19)

Rat (10)

Bovine (5)

Dog (2)

Gibbon (3)

Hamster (3)

Horse (4)

Monkey (4)

Orangutan (3)

Pig (4)

Primate (6)

Rabbit (1)

Sheep (5)

more less

Application

IHC (25)

IHC-P (14)

WB (32)

Flo (1)

ELISA (16)

IF (2)

IP (3)

Peptide-ELISA (3)

Host

rabbit (27)

mouse (4)

goat (1)

Product Group

IHCPlus (3)

Isotype

IgG (15)

IgG1,k (2)

IgG2a,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (28)

Clone

5-2H10 (1)

AG103 (1)

FT62-6 (1)

FT86-4 (1)

Format

APC Conjugated (1)

Biotin Conjugated (3)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (20)

Epitope

aa1-30 (7)

N-Terminus (5)

C-Terminus (4)

N-Terminal (1)

aa19-68 (1)

aa400-505 (1)

aa464-477 (1)

Publications

No (31)

Yes (1)

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FTO Antibody (N-Terminus) LS-B5891

(4.0) Rating

(1) Publication(s)

Antibody:

FTO Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

FTO Antibody (N-Terminus, HRP) LS-C449991

Antibody:

FTO Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Sheep, Bovine, Rat, Hamster, Pig, Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

FTO Antibody (N-Terminus, Biotin) LS-C449989

Antibody:

FTO Rabbit anti-Mouse Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Sheep, Bovine, Rat, Hamster, Pig, Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

FTO Antibody (N-Terminus, FITC) LS-C449990

Antibody:

FTO Rabbit anti-Mouse Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Mouse, Sheep, Bovine, Rat, Hamster, Pig, Horse, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

IHC-plus™ FTO Antibody (clone 5-2H10) LS-B7982

(4.0) Rating

Antibody:

FTO Mouse anti-Rat Monoclonal (5-2H10) Antibody

Reactivity:

Mouse, Dog, Sheep, Bovine, Rat, Horse, Primate, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

FTO Antibody (clone FT62-6) LS-C344911

Antibody:

FTO Mouse anti-Mouse Monoclonal (FT62-6) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$354; 100 µg/$407

Select

IHC-plus™ FTO Antibody (aa400-505) LS-B7788

(4.0) Rating

Antibody:

FTO Rabbit anti-Human Polyclonal (aa400-505) Antibody

Reactivity:

Mouse, Human, Primate

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

Select

FTO Antibody (C-Terminus, Biotin) LS-C141700

Antibody:

FTO Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Human, Primate

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

FTO Antibody (C-Terminus, DY550) LS-C141704

Antibody:

FTO Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody

Reactivity:

Mouse, Human, Primate

Applications:

IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

Select

FTO Antibody (C-Terminus, DY650) LS-C141701

Antibody:

FTO Rabbit anti-Human Polyclonal (C-Terminus) (DY650) Antibody

Reactivity:

Mouse, Human, Primate

Applications:

IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY550
• DY650

• Unconjugated
• Biotin
• DY550
• More...
  • DY650

Select

FTO Antibody (clone AG103) LS-C344739

Antibody:

FTO Mouse anti-Human Monoclonal (AG103) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$354; 100 µg/$407

Select

FTO Antibody LS-C345023

Antibody:

FTO Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$323

Select

FTO Antibody LS-C108502

Antibody:

FTO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

FTO Antibody (aa1-30) LS-C166270

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

FTO Antibody LS-C401694

Antibody:

FTO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

FTO Antibody LS-C404996

Antibody:

FTO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

FTO Antibody (aa1-30) LS-C327412

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

FTO Antibody (aa1-30, HRP) LS-C546275

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

FTO Antibody (aa1-30, Biotin) LS-C526163

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

FTO Antibody (aa1-30, FITC) LS-C244436

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

FTO Antibody (aa1-30, APC) LS-C244435

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

FTO Antibody (aa1-30, PE) LS-C244438

Antibody:

FTO Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

FTO Antibody LS-C827807

Antibody:

FTO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

FTO Antibody LS-C833293

Antibody:

FTO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

FTO Antibody (clone FT86-4) LS-C344899

Antibody:

FTO Mouse anti-Human Monoclonal (FT86-4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

50 µg/$337; 100 µg/$386

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