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EPHB4 / EPH Receptor B4

EPH receptor B4

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Gene Name: EPH receptor B4
Family/Subfamily: Protein Kinase , Ephrin Receptor
Synonyms: EPHB4, EPH receptor B4, Ephrin receptor EphB4, Ephrin type-B receptor 4, HTK, MYK1, TYRO11, Soluble EPHB4 variant 1, Soluble EPHB4 variant 3, Hepatoma transmembrane kinase, MDK2, Soluble EPHB4 variant 2, Tyrosine-protein kinase TYRO11
Target Sequences: NM_004444 NP_004435.3 P54760

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Products
Antibodies (72)
Primary (72)
EPHB4 / EPH Receptor B4 (72)
Human (58)
Mouse (23)
Rat (2)
Bovine (1)
Dog (1)
Pig (1)
IHC (20)
IHC-Fr (1)
IHC-P (8)
WB (50)
Flo (10)
ELISA (48)
ICC (4)
IF (9)
IP (6)
Peptide-ELISA (3)
rabbit (35)
mouse (35)
goat (1)
rat (1)
Product Group
IHCPlus (2)
IgG (17)
IgG1 (7)
IgG1,k (19)
IgG2a (4)
IgG2a,k (1)
monoclonal mc (37)
polyclonal pc (35)
039 (1)
1D1 (1)
3D7G8 (1)
5B5 (2)
5B8F7 (2)
67CT23.5.8 (1)
7H4A6 (2)
VEB-7E4 (1)
APC Conjugated (6)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (6)
HRP Conjugated (4)
PE Conjugated (6)
Preservative Free (2)
Unconjugated (46)
aa360-389 (7)
C-Terminus (2)
540-620 aa, Internal (1)
Amino Acid: 562-612 (1)
Extracellular (1)
Internal (1)
aa566-578 (1)
aa571-620 (1)
aa580-630 (1)
aa889-923 (1)
aa967-1000 (1)
No (72)
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (C-Terminus) (3D7G8) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$737
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, IP, WB
HRP Conjugated
100 µl/$982
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, IP, WB
Biotin Conjugated
100 µl/$982
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, IP, WB
FITC Conjugated
100 µl/$982
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, IP, WB
APC Conjugated
100 µl/$982
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, IP, WB
PE Conjugated
100 µl/$982
EPHB4 / EPH Receptor B4 Antibody - Anti-EPHB4 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (Extracellular) (5B5) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
EPHB4 / EPH Receptor B4 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EPHB4 / EPH Receptor B4 Rabbit anti-Human Polyclonal (aa580-630) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
EPHB4 / EPH Receptor B4 Antibody - IHC of paraffin-embedded Human pancreas carcinoma (left) and breast carcinoma (right) tissue, showing membrane and cytoplasmic (pancreas carcinoma) localization, membrane (breast carcinoma) localization using EphB4 mouse
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (5B8F7) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$331
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EPHB4 / EPH Receptor B4 Rat anti-Mouse Monoclonal (VEB-7E4) Antibody
Mouse
Flo, IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$723
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EPHB4 / EPH Receptor B4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo, ICC, IF
PE Conjugated
25 Tests/$293; 100 Tests/$376
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, ICC, IF
FITC Conjugated
25 Tests/$278; 100 Tests/$346
EPHB4 / EPH Receptor B4 Antibody - Western blot using EphB4 mouse monoclonal antibody against Jurkat (1) and HEK293 (2) cell lysate.
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (7H4A6) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$403
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EPHB4 / EPH Receptor B4 Rabbit anti-Mouse Monoclonal (Preservative Free) (039) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
EPHB4 / EPH Receptor B4 Antibody - Western blot of anti-EPHB4 Monoclonal Antibody by EPHB4 recombinant protein(Fragment). EPHB4 protein (arrow) was detected using the purified antibody.
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (67CT23.5.8) Antibody
Human
WB
Unconjugated
400 µl/$393
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC, IF
Unconjugated
100 µl/$412
Select
EPHB4 / EPH Receptor B4 Rabbit anti-Human Polyclonal (PE) Antibody
Human
Flo
PE Conjugated
25 Tests/$293; 100 Tests/$376
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EPHB4 / EPH Receptor B4 Goat anti-Human Polyclonal (aa566-578) Antibody
Dog, Bovine, Pig, Human
Peptide-ELISA
Unconjugated
100 µg/$401
EPHB4 / EPH Receptor B4 Antibody - Western blot of EphB4 antibody
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EPHB4 / EPH Receptor B4 Rabbit anti-Human Polyclonal (540-620 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
EPHB4 / EPH Receptor B4 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
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EPHB4 / EPH Receptor B4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
EPHB4 / EPH Receptor B4 Antibody - EphB4 Antibody in Immunofluorescence (IF)
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal (5B5) Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$541
EPHB4 / EPH Receptor B4 Antibody - Confocal Immunofluorescence (IF) analysis of methanol-fixed HEK293 cells trasfected with EphB4-hIgGFc using EphB4 Monoclonal Antibody (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
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EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
EPHB4 / EPH Receptor B4 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
EPHB4 / EPH Receptor B4 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Pancreas carcinoma (left) and breast carcinoma (right) tissue, showing membrane and cytoplasmic (pancreas carcinoma) localization, membrane (breast carcinoma) localization with DAB staining using Ep.
Select
EPHB4 / EPH Receptor B4 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Viewing 1-25 of 72 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).