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CYCS / Cytochrome c
cytochrome c, somatic
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
| Gene Name: | cytochrome c, somatic |
| Synonyms: | CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic |
| Target Sequences: | NM_018947 NP_061820.1 P99999 |
Publications (3)
1
Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease. She P, Zhang Z, Marchionini D, Diaz WC, Jetton TJ, Kimball SR, Vary TC, Lang CH, Lynch CJ. American journal of physiology. Endocrinology and metabolism. 2011 301:E49-61.
[PubMed:21505144]
[PMC:PMC3129844]
Related Antibodies: LS-C41042.
2
Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species. McGuire KA, Barlan AU, Griffin TM, Wiethoff CM. Journal of virology. 2011 85:10806-13.
[PubMed:21835790]
[PMC:PMC3187480]
Related Antibodies: LS-C41042.
3
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Emilie Barruet , Steven M Garcia , Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz. eLife. 2020 Apr;9:e51576. [Full Text Article]
[PubMed:32234209]
[PMC:PMC7164960]
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Antibodies
(135)
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(135)
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(23)
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(3)
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CYCS / Cytochrome c
(182)
Reactivity
Human
(127)
Mouse
(100)
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(110)
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(6)
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(14)
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(16)
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(5)
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(3)
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(2)
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(28)
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(29)
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(68)
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(39)
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(5)
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(2)
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(19)
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monoclonal mc
(63)
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(72)
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(3)
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ABM30D4
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(3)
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(4)
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(23)
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(1)
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(9)
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(9)
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(1)
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(7)
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(1)
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(4)
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(1)
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(81)
Epitope
aa13-99
(9)
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(8)
aa5-100
(8)
aa10-59
(5)
aa91-105
(4)
aa2-105
(2)
aa66-104
(2)
C-Terminus
(1)
His19
(1)
N-Terminus
(1)
aa1-188
(1)
aa1-80, aa81-104, aa66-104
(1)
aa21-55
(1)
aa55-105
(1)
Publications
No
(181)
Yes
(1)
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(1)
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(8)
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(20)
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(20)
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(13)
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(2)
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(1)
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(2)
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(1)
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(4)
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(1)
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(9)
Mouse
(2)
Source
293T Cells
(1)
E. coli
(7)
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(3)
Wheat Germ Extract
(2)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(2)
CYCS / Cytochrome c Mouse anti-Horse Monoclonal (7H8.2C12) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$485
CYCS / Cytochrome c Mouse anti-Pigeon Monoclonal (aa1-80) (7H8.2C12) Antibody
Pigeon, Drosophila, Horse, Mouse, Rat, Hamster, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$685
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
E. coli
GST, N-terminus
39.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CYCS / Cytochrome c Mouse anti-Horse Monoclonal (7H8.2C12) Antibody
Mouse, Rat, Horse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CYCS / Cytochrome c Mouse anti-Mouse Monoclonal (6H2.B4) Antibody
Mouse, Rat, Human
Flo, IF, IP, WB
Unconjugated
25 µg/$264; 100 µg/$342
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Porcine
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CYCS / Cytochrome c Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$460
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Ready-to-Use) (7H8.2C12 + CYCS/1010) Antibody
Rat, Pig, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
HEK 293 Cells
Myc-DDK (Flag)
11.6 kDa
20 µg/$1,107
CYCS / Cytochrome c Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, IF, IP
Unconjugated
100 µg/$801
CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, ID, IE, WB
Unconjugated
5 mg/$558
CYCS / Cytochrome c Sheep anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human
IF, IP, WB
Unconjugated
100 µg/$842
CYCS / Cytochrome c Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
CYCS / Cytochrome c Mouse anti-Human Monoclonal (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Mouse anti-Human Monoclonal (15F10) Antibody
Mouse, Rat, Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Azide-free, BSA-free) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Mouse anti-Human Monoclonal (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Ready-to-Use) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
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product results
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