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CELA1 / Pancreatic Elastase 1

chymotrypsin-like elastase family, member 1

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.

Gene Name: chymotrypsin-like elastase family, member 1
Family/Subfamily: Protease , Serine S1
Synonyms: CELA1, El1a, Elastase I, ELA1, Elastase 1, pancreatic, Elastase-1, Pancreatic elastase, Pancreatic elastase I, Porcine pancreatic elastase, Pancreatic elastase 1, Elastase
Target Sequences: NM_001971 NP_001962.3 Q9UNI1

Publications (1)

1
STING signalling protects against chronic pancreatitis by modulating Th17 response. Qinglan Zhao , Murli Manohar , Yi Wei, Stephen J Pandol, Aida Habtezion. Gut. 2019 October;68:1827-1837. [Full Text Article] [PubMed:30705050] [PMC:PMC7069765]

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Products
Antibodies (40)
Primary (40)
CELA1 / Pancreatic Elastase 1 (40)
Human (25)
Mouse (24)
Rat (12)
Bat (3)
Bovine (3)
Gibbon (3)
Monkey (3)
Pig (10)
Rabbit (3)
IHC (5)
IHC-P (1)
WB (39)
ELISA (15)
IF (2)
rabbit (39)
mouse (1)
Product Group
IHCPlus (1)
IgG (17)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (39)
4H5 (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (7)
Liquid (3)
Lyophilized (3)
PE Conjugated (3)
Unconjugated (11)
aa40-258 (8)
aa44-259 (8)
aa51-79 (7)
N-Terminus (4)
aa80-129 (4)
No (40)
CELA1 / Pancreatic Elastase 1 Antibody - Anti-CELA1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CELA1 / Pancreatic Elastase 1 Mouse anti-Human Monoclonal (4H5) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
CELA1 / Pancreatic Elastase 1 Antibody - Anti-Elastase and Anti-Insulin Antibodies - Immunofluorescence. Double immunofluorescence microscopy after staining of mouse embryonic gut tissue with anti-Elastase antibody and anti-Insulin antibody. Tissue sections were prepared using frozen sections after fixation for 1 h in 4% PFA. The image shows elastase staining in green and insulin staining in red. Personal communication, C. Murtaugh, Harvard University.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Lyophilized) Antibody
Pig
ELISA, IF, WB
Unconjugated, Lyophilized
100 µg/$567
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Lyophilized) (HRP) Antibody
Pig
ELISA, IHC, WB
HRP Conjugated, Lyophilized
100 µg/$552
CELA1 / Pancreatic Elastase 1 Antibody - CELA1 Antibody western blot of A2058 cell line lysates (35 ug/lane). The CELA1 antibody detected the CELA1 protein (arrow).
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) Antibody
Human
WB
Unconjugated
400 µl/$393
CELA1 / Pancreatic Elastase 1 Antibody - CELA1 antibody Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa80-129) Antibody
Mouse
WB
Unconjugated
100 µl/$424
CELA1 / Pancreatic Elastase 1 Antibody - CELA1 antibody Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa80-129) (HRP) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CELA1 / Pancreatic Elastase 1 Antibody - CELA1 antibody Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa80-129) (Biotin) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CELA1 / Pancreatic Elastase 1 Antibody - CELA1 antibody Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa80-129) (FITC) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
CELA1 / Pancreatic Elastase 1 Antibody - Western blot of recombinant CELA1 / Elastase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa44-259) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
CELA1 / Pancreatic Elastase 1 Antibody - Western blot of recombinant CELA1 / Elastase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa44-259) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
CELA1 / Pancreatic Elastase 1 Antibody - Western blot of recombinant CELA1 / Elastase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Mouse Polyclonal (aa44-259) (Cy3) Antibody
Mouse, Rat
WB
Cy3 Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
CELA1 / Pancreatic Elastase 1 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal Antibody
Pig
ELISA, IHC, WB
Unconjugated
2 ml/$1,225
CELA1 / Pancreatic Elastase 1 Antibody - Double immunofluorescence microscopy of rabbit anti-Elastase antibody and anti-Insulin antibody. Tissue: mouse embryonic gut tissue. Fixation: 1 h in 4% PFA. Antigen retrieval: not required. Primary antibody: antibodies at 10 µg/mL for 1 h at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: elastase is secreted, extracellular. Staining: elastase as green fluorescent signal with insulin staining in red.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Liquid) Antibody
Pig
ELISA, IF, WB
Unconjugated, Liquid
25 µl/$304
CELA1 / Pancreatic Elastase 1 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using CELA1 Polyclonal Antibody at dilution of 1:70(×200)
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Liquid) (HRP) Antibody
Pig
ELISA, IHC, WB
HRP Conjugated, Liquid
25 µl/$304
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa51-79) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Lyophilized) (Biotin) Antibody
Pig
ELISA, WB
Biotin Conjugated, Lyophilized
100 µg/$552
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Pig Polyclonal (Liquid) (Biotin) Antibody
Pig
ELISA, WB
Biotin Conjugated, Liquid
25 µl/$304
CELA1 / Pancreatic Elastase 1 Antibody - Western blot of CELA1 / Pancreatic Elastase 1 antibody.
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CELA1 / Pancreatic Elastase 1 Rabbit anti-Human Polyclonal (aa40-258) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).