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CD86

CD86 molecule

CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Gene Name: CD86 molecule
Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2
Target Sequences: NM_006889 NP_008820.3 P42081

Publications (1)

1
N-docosahexaenoylethanolamine reduces neuroinflammation and cognitive impairment after mild traumatic brain injury in rats. Arina I Ponomarenko, Anna A Tyrtyshnaia, Evgeny A Pislyagin, Inessa V Dyuizen, Ruslan M Sultanov, Igor V Manzhulo. Scientific reports. 2021 January;11:756. [Full Text Article] [PubMed:33436960] [PMC:PMC7804312]

☰ Filters
Antibodies (194)
Proteins (33)
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CD86 (245)
Human (124)
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rabbit (68)
mouse (71)
rat (55)
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monoclonal mc (126)
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CD86 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD86 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
CD86 Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with CD86 antibody (C86/1146).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CD86 Mouse anti-Human Monoclonal (C86/1146) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CD86 Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with CD86 antibody (C86/1146).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD86 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (C86/1146) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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CD86 Mouse anti-Human Monoclonal (BU63) Antibody
Human
Flo, Func, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$309
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CD86 Mouse anti-Human Monoclonal (BU63) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
25 µg/$281; 0.2 mg/$471
Select
CD86 Mouse anti-Human Monoclonal (FITC) (BU63) Antibody
Human
Flo, Func, IHC-Fr, IP, WB
FITC Conjugated
100 Tests/$337
CD86 Antibody - Surface staining of human peripheral blood cells with anti-CD86 (BU63) PerCP (monocyte gate).
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CD86 Mouse anti-Human Monoclonal (PerCP) (BU63) Antibody
Human
Flo, Func, IHC-Fr, IP, WB
PerCP Conjugated
100 Tests/$365
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CD86 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µl/$412
CD86 Antibody - IHC testing of FFPE human melanoma with CD86 antibody (clone CDLA86).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD86 Mouse anti-Human Monoclonal (CDLA86) Antibody
Human
IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CD86 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
CD86 Antibody - Human peripheral blood monocytes stained with IT2.2 PE.
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CD86 Mouse anti-Human Monoclonal (IT2.2) Antibody
Human, Monkey, Baboon
Flo, IHC, IHC-Fr, WB
Unconjugated
25 µg/$261; 100 µg/$331
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CD86 Rat anti-Mouse Monoclonal (GL-1) Antibody
Mouse
Flo, Func, ICC, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$267
CD86 Antibody - Bovine peripheral blood lymphocytes stained with Mouse anti-Bovine CD86 followed by Goat anti-Mouse IgG:FITC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD86 Mouse anti-Bovine Monoclonal (RPE) (IL-A190) Antibody
Bovine
Flo
RPE Conjugated
100 Tests/$589
CD86 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$669
Select
CD86 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
200 µg/$732
CD86 Antibody - IHC testing of human esophageal tumor stained with CD86 antibody (BU63).
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CD86 Mouse anti-Human Monoclonal (BU63) Antibody
Mouse, Rat, Human
Flo, IF, WB
Unconjugated
20 µg/$371; 100 µg/$574
CD86 Antibody - CD86 antibody BU63 immunohistochemistry This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD86 Mouse anti-Human Monoclonal (Ready-to-Use) (BU63) Antibody
Mouse, Rat, Human
IHC
Unconjugated, Ready-to-Use
7 ml/$574
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CD86 Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (GL1) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$427
CD86 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CD86 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD86 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
Select
CD86 Mouse anti-Human Monoclonal (Azide-free) (BU63) Antibody
Human
ELISA, Flo, Func, WB
Unconjugated, Azide-free
100 µg/$446
Select
CD86 Rat anti-Mouse Monoclonal (APC) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
APC Conjugated
100 µg/$558
Select
CD86 Mouse anti-Rat Monoclonal (24F) Antibody
Rat
Flo, IHC, IHC-Fr, IP
Unconjugated
25 µg/$285; 0.1 mg/$395; 0.25 mg/$486
CD86 Antibody - Immunofluorescence staining of B7-2 in Raji cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-human B7-2 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
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CD86 Rabbit anti-Human Monoclonal (Preservative Free) (103) Antibody
Human
ELISA, ICC, IF
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
Viewing 1-25 of 245 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).