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Catalog Number	Size	Price
LS-C188424-25	25 µg (1 mg/ml)	$285
LS-C188424-0.1	0.1 mg (1 mg/ml)	$395
LS-C188424-0.25	0.25 mg (1 mg/ml)	$486

Monoclonal Mouse anti‑Rat CD86 Antibody (clone 24F, IHC) LS‑C188424

Name: Anti-CD86 Antibody | Mouse anti-Rat Monoclonal Flo,IHC,IP | LSBio
Brand: Lifespan BioSciences
SKU: LS-C188424-25
Price: 285.0000 USD
Availability: InStock

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Antibody:

CD86 Mouse anti-Rat Monoclonal (24F) Antibody

Application:

IHC, IHC-Fr, IP, Flo

Reactivity:

Rat

Format:

Unconjugated, Unmodified

$285

LS-C188424-25

$395

LS-C188424-0.1

$486

LS-C188424-0.25

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

CD86 Mouse anti-Rat Monoclonal (24F) Antibody

Application:

IHC, IHC-Fr, IP, Flo

Reactivity:

Rat

Format:

Unconjugated, Unmodified

Specifications

Description

CD86 antibody LS-C188424 is an unconjugated mouse monoclonal antibody to rat CD86. Validated for Flow, IHC and IP.

Target

Rat CD86

Synonyms

CD86 | Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2

See All CD86 Antibodies

Host

Mouse

Reactivity

Rat (tested or 100% immunogen sequence identity)

Clonality

IgG1 Monoclonal

Clone

24F

Conjugations

Unconjugated

Purification

Protein G purified

Modifications

Unmodified

Immunogen

HTLV-1 transformed Lewis - S1 cells.

Specificity

Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.

Applications

IHC
IHC - Frozen
Immunoprecipitation
Flow Cytometry (1:25 - 1:200)

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Presentation

PBS, 0.09% Sodium Azide

Storage

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About CD86

Uniprot: P42081 NCBI: NM_006889 NP_008820.3