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CAPN1 / Calpain 1
calpain 1, (mu/I) large subunit
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
| Gene Name: | calpain 1, (mu/I) large subunit |
| Family/Subfamily: | Protease , Cysteine C2 |
| Synonyms: | CAPN1, Calpain i, Calpain mu-type, Calpain, large polypeptide L1, Calpain-1 catalytic subunit, Calpain 1, Calpain-1 large subunit, CANP, CANP1, Mu CANP, Mu-calpain, Mu-type calpain, MuCANP, Micromolar-calpain, MuCL, CANP 1, CANPL1 |
| Target Sequences: | BC008751 AAH08751.1 P07384 |
Publications (1)
1
Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment. Yubin Wang, Yan Liu, Amy Nham, Arash Sherbaf, Diana Quach, Emad Yahya, Davis Ranburger, Xiaoning Bi, Michel Baudry. Science advances. 2020 July;6: [Full Text Article]
[PubMed:32937436]
[PMC:PMC7458466]
Related Antibodies: LS-B4768.
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CAPN1 / Calpain 1
(122)
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(1)
CAPN1 / Calpain 1 Mouse anti-Bovine Monoclonal (15C10) Antibody
Mouse, Bovine, Rat, Human
ELISA, IHC-P, IP, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
E. coli
6His, N-terminus
85.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CAPN1 / Calpain 1 Goat anti-Human Polyclonal (aa515-526) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
E. coli
6His, N-terminus
31.8 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
CAPN1 / Calpain 1 Mouse anti-Human Monoclonal (aa1-420) (1376CT809.24.85) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
CAPN1 / Calpain 1 Goat anti-Human Polyclonal (aa468-481) Antibody
Xenopus, Pig, Rabbit, Goat, Guinea pig, Bovine, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa75-343) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa313-327) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$575
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa20-330) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CAPN1 / Calpain 1 Mouse anti-Bovine Monoclonal Antibody
Bovine
ELISA, ICC, IHC, IP, WB
Unconjugated
100 µl/$786
CAPN1 / Calpain 1 Mouse anti-Human Monoclonal (1E6G9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
E. coli
His
30.7 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa20-330) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$394
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa312-326) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal (aa396-555) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
CAPN1 / Calpain 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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