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BrdU
Bromodeoxyuridine (BrdU)
Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd) is a synthetic nucleoside that is an analog of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues. 5-Bromodeoxycytidine is deaminated to form BrdU. BrdU can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle during which DNA is replicated), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical (see immunohistochemistry), thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat. BrdU can be passed to daughter cells upon replication. BrdU has been demonstrated to be detectable over two years post-infusion.
BrdU Target Details
| Target Name: | Bromodeoxyuridine (BrdU) |
Publications (11)
1
Intrastriatal transforming growth factor alpha delivery to a model of Parkinson's disease induces proliferation and migration of endogenous adult neural progenitor cells without differentiation into dopaminergic neurons. Cooper O, Isacson O. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 24:8924-31.
[PubMed:15483111]
[PMC:PMC2613225]
2
Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: dual role of replication and transcription activator. Wang Y, Tang Q, Maul GG, Yuan Y. Journal of virology. 2006 80:12171-86. (ICC)
[PubMed:17020951]
[PMC:PMC1676287]
3
CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes. Tokuda M, Kadokawa Y, Kurahashi H, Marunouchi T. Biology of reproduction. 2007 76:130-41. (ICC)
[PubMed:17035642]
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BrdU Rabbit Polyclonal Antibody
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$567
BrdU Mouse Monoclonal (MoBU-1) Antibody
Human
Flo, IHC
Unconjugated
100 µg/$287
BrdU Rat Monoclonal (2H8) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Rabbit Polyclonal Antibody
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
25 µl/$304
BrdU Mouse Monoclonal (B33.1) Antibody
Human
IHC
Unconjugated
0.5 ml/$328
BrdU Mouse Monoclonal (2G6) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (7H4) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (7F12) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (4H10) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (1C7) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (4A3) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (2B5) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (29G6.E8) Antibody
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$574
BrdU Mouse Monoclonal (3A4) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (2B12) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Mouse Monoclonal (5C1) Antibody
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$434
BrdU Rabbit anti-Synthetic Polyclonal Antibody
Synthetic
Flo, ICC, IF, IHC-P
Unconjugated
50 µg/$448
BrdU Mouse anti-Synthetic Monoclonal (Bu20a) Antibody
Synthetic
Flo, IF, IHC, IHC-Fr, IHC-P
Unconjugated
20 µg/$285; 0.1 mg/$395; 0.2 mg/$486
BrdU Mouse Monoclonal (MoBu-1) Antibody
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
BrdU Mouse Monoclonal (Azide-free, BSA-free) (MoBu-1) Antibody
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
BrdU Mouse Monoclonal (85-2C8) Antibody
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
BrdU Mouse Monoclonal (Azide-free, BSA-free) (85-2C8) Antibody
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
BrdU Mouse Monoclonal (BRD.3) Antibody
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
BrdU Mouse Monoclonal (Azide-free, BSA-free) (BRD.3) Antibody
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
BrdU Mouse Monoclonal (Azide-free, BSA-free) (BU20a) Antibody
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
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