ATXN2 / SCA2 / Ataxin-2

ataxin 2

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12, and it has been determined that the diseased allele contains 37-50 CAG repeats, compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.

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Products

Antibodies (26)

ELISA Kits (8)

Proteins (1)

Type

Primary (26)

Recombinant (1)

Sandwich (8)

Target

ATXN2 / SCA2 / Ataxin-2 (35)

Reactivity

Human (26)

Mouse (12)

Rat (9)

Bat (5)

Bovine (5)

Chicken (4)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (6)

Hamster (1)

Horse (5)

Monkey (6)

Pig (5)

Porcine (1)

Rabbit (1)

Sheep (2)

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IHC (9)

IHC-P (4)

WB (21)

ELISA (7)

IF (5)

IP (3)

Peptide-ELISA (6)

Host

rabbit (24)

goat (1)

rabbit-new zealand white (1)

Product Group

IHCPlus (1)

Isotype

IgG (14)

Clonality

polyclonal pc (26)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (7)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (20)

Epitope

C-Terminus (3)

700-780 aa, Internal (1)

Internal (1)

Phe774 (1)

aa1262-1312 (1)

aa1283-1313 (1)

aa1293-1313 (1)

aa321-355 (1)

aa479-489 (1)

aa721-780 (1)

aa725-757 (1)

aa725-774 (1)

aa731-780 (1)

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Publications

No (35)

Sample Type

Plasma (4)

Serum (4)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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ATXN2 / SCA2 / Ataxin-2 Antibody LS-C501686

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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ATXN2 / SCA2 / Ataxin-2 Antibody (Biotin) LS-C501676

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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ATXN2 / SCA2 / Ataxin-2 Antibody (FITC) LS-C501678

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

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ATXN2 / SCA2 / Ataxin-2 Antibody (aa725-774) LS-C200163

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa725-774) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (aa479-489) LS-C113029

Antibody:

ATXN2 / SCA2 / Ataxin-2 Goat anti-Human Polyclonal (aa479-489) Antibody

Applications:

IF, IHC, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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Human ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F37826

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F38254

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Monkey ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41515

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Rat ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F38586

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (Internal) LS-C352811

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$299

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ATXN2 / SCA2 / Ataxin-2 Antibody (700-780 aa, Internal) LS-C382160

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (700-780 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (aa1262-1312) LS-C287945

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa1262-1312) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

IHC-plus™ ATXN2 / SCA2 / Ataxin-2 Antibody (aa721-780) LS-B16827

(4.0) Rating

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa721-780) Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C664373

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (C-Terminus, HRP) LS-C436638

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (C-Terminus, Biotin) LS-C436075

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• HRP
• Biotin

• HRP
• Biotin

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C833827

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (aa1283-1313) LS-C407696

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa1283-1313) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C490159

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C804820

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C829277

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (Phe774) LS-C192113

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (Phe774) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (aa1293-1313) LS-C313216

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa1293-1313) Antibody

Reactivity:

Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

ATXN2 / SCA2 / Ataxin-2 Antibody LS-C823829

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ATXN2 / SCA2 / Ataxin-2 Antibody (aa731-780) LS-C119747

Antibody:

ATXN2 / SCA2 / Ataxin-2 Rabbit anti-Human Polyclonal (aa731-780) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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