Target
Human ATXN2 / SCA2 / Ataxin-2
Synonyms
ATXN2 | ASL13 | Ataxin 2 | ATX2 | Ataxin-2 | SCA2 | TNRC13
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Sheep
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human ATX2 (1283-1313 aa QSALQPIPVSTTAHFPYMTHPSVQAHHQQQL), identical to the related mouse sequence.
Specificity
Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- Western blot (0.1 - 0.5 µg/ml)
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Usage
IHC: Antigen retrieval by boiling the paraffin sections in 10 mM citrate buffer, pH6.0, for 20 minutes is required for the staining of formalin/paraffin sections.
Presentation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg sodium azide.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ATXN2 / SCA2 / Ataxin-2