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APOE / Apolipoprotein E
apolipoprotein E
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
| Gene Name: | apolipoprotein E |
| Synonyms: | APOE, AD2, Apo-E, Apolipoprotein E3, Apolipoprotein E, LDLCQ5, LPG |
| Target Sequences: | NM_000041 NP_000032.1 P02649 |
Publications (2)
1
A proteomic approach for the diagnosis of bacterial meningitis. Jesse S, Steinacker P, Lehnert S, Sdzuj M, Cepek L, Tumani H, Jahn O, Schmidt H, Otto M. PloS one. 2010 5:e10079. (WB)
[PubMed:20386697]
[PMC:PMC2851643]
2
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model. Leticia Rodrigues, Krista Minéia Wartchow, Michael Buchfelder, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Andrea Kleindienst. International journal of molecular sciences. 2022 August;23: [Full Text Article]
[PubMed:36076994]
[PMC:PMC9455494]
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APOE / Apolipoprotein E
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Publications
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(140)
Neuroscience
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
Neuroscience
APOE / Apolipoprotein E Goat anti-Human Polyclonal (aa305-317) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Neuroscience
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IHC, IHC-Fr
Unconjugated
1 ml/$549
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (Biotin) (WUE-4) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (DY488) (WUE-4) Antibody
Human
ELISA, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
APOE / Apolipoprotein E Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$838
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$626
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (1F9) Antibody
Human
IHC, IP, WB
Unconjugated
100 µg/$454
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Neuroscience
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (aa100-150) (4E4) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (aa100-150) (DY650) (4E4) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
DY650 Conjugated
0.1 ml/$416
Neuroscience
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (aa140-160) (8B65) Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µl/$725
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (Low Endotoxin) (WUE-4) Antibody
Human
ELISA, WB
Unconjugated, Low Endotoxin
0.5 mg/$697
Neuroscience
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC-P
Unconjugated
50 µg/$460
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (1H4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (aa263-292) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
APOE / Apolipoprotein E Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$891
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (WUE-4) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$486; 0.2 mg/$556
Neuroscience
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IHC-P, IP, WB
Unconjugated
0.5 mg/$440
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