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Catalog Number Size Price
LS-B13235-0.5 0.5 mg (6.21 mg/ml) $440 
APOE / Apolipoprotein E Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
APOE / Apolipoprotein E Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
APOE / Apolipoprotein E Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
APOE / Apolipoprotein E Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Polyclonal Goat anti‑Human APOE / Apolipoprotein E Antibody (IHC, WB) LS‑B13235

PathPlus™ Polyclonal Goat anti‑Human APOE / Apolipoprotein E Antibody (IHC, WB) LS‑B13235

Note: This antibody replaces LS-C316474
Antibody:
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB, IP, Flo, ELISA, ID
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B13235-0.5
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB, IP, Flo, ELISA, ID
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Apolipoprotein E (APOE) is a main apoprotein of the chylomicron that binds to a specific receptor on liver cells and peripheral cells. It functions in fat metabolism and is thought to be involved in the progression of Alzheimer’s disease and cardiovascular disease. It is an essential protein for the normal catabolism of triglyceride-rich lipoprotein constituents. Mutations in APOE result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. APOE mutations are also implicated in atherosclerosis, multiple sclerosis, and impaired hippocampal development and cognitive function. In immunohistochemistry of normal tissue, APOE has cytoplasmic and plasma positivity in renal tubules, Leydig cells, hepatocytes, the adrenal gland, and in subsets of neurons throughout the brain. References: Neurology. 63 (10): 1898–901, PMID: 15557508; Science. 240 (4852): 622–30, PMID: 3283935; Science. 240 (4852): 622–30, PMID: 3283935; Science. 261 (5123): 921–23. doi:10.1126/science.8346443. PMID 8346443
Target
Human APOE / Apolipoprotein E
Synonyms
APOE | AD2 | Apo-E | Apolipoprotein E3 | Apolipoprotein E | LDLCQ5 | LPG
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Human apolipoprotein E.
Specificity
Human Apolipoprotein E
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
  • Immunodiffusion
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
This antibody is suitable for all immunoassay applications. The optimal working dilution should be determined by the investigator.
Presentation
10 mM Sodium Phosphate, pH 7.2, 0.15 M NaCl, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About APOE / Apolipoprotein E
P02649 NM_000041 NP_000032.1

Validation

APOE / Apolipoprotein E Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

APOE / Apolipoprotein E Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ APOE / Apolipoprotein E Antibody for IHC, WB/Western, IP, Flow, ELISA LS-B13235 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/22/2024